1rrk: Difference between revisions

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[[Image:1rrk.jpg|left|200px]]<br /><applet load="1rrk" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1rrk.jpg|left|200px]]
caption="1rrk, resolution 2.00&Aring;" />
 
'''Crystal Structure Analysis of the Bb segment of Factor B'''<br />
{{Structure
|PDB= 1rrk |SIZE=350|CAPTION= <scene name='initialview01'>1rrk</scene>, resolution 2.00&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene> and <scene name='pdbligand=CO:COBALT (II) ION'>CO</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Alternative-complement-pathway_C3/C5_convertase Alternative-complement-pathway C3/C5 convertase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.47 3.4.21.47]
|GENE= BF ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Crystal Structure Analysis of the Bb segment of Factor B'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1RRK is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=IOD:'>IOD</scene>, <scene name='pdbligand=NA:'>NA</scene> and <scene name='pdbligand=CO:'>CO</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Alternative-complement-pathway_C3/C5_convertase Alternative-complement-pathway C3/C5 convertase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.47 3.4.21.47] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RRK OCA].  
1RRK is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RRK OCA].  


==Reference==
==Reference==
Structural analysis of engineered Bb fragment of complement factor B: insights into the activation mechanism of the alternative pathway C3-convertase., Ponnuraj K, Xu Y, Macon K, Moore D, Volanakis JE, Narayana SV, Mol Cell. 2004 Apr 9;14(1):17-28. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15068800 15068800]
Structural analysis of engineered Bb fragment of complement factor B: insights into the activation mechanism of the alternative pathway C3-convertase., Ponnuraj K, Xu Y, Macon K, Moore D, Volanakis JE, Narayana SV, Mol Cell. 2004 Apr 9;14(1):17-28. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15068800 15068800]
[[Category: Alternative-complement-pathway C3/C5 convertase]]
[[Category: Alternative-complement-pathway C3/C5 convertase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: factor b]]
[[Category: factor b]]


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