1rt6: Difference between revisions

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[[Image:1rt6.gif|left|200px]]<br /><applet load="1rt6" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1rt6.gif|left|200px]]
caption="1rt6, resolution 2.8&Aring;" />
 
'''HIV-1 REVERSE TRANSCRIPTASE COMPLEXED WITH UC38'''<br />
{{Structure
|PDB= 1rt6 |SIZE=350|CAPTION= <scene name='initialview01'>1rt6</scene>, resolution 2.8&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene> and <scene name='pdbligand=UC3:1-METHYL ETHYL 2-CHLORO-5-[[[(1-METHYLETHOXY)THIOOXO]METHYL]AMINO]-BENZOATE'>UC3</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/RNA-directed_DNA_polymerase RNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.49 2.7.7.49]
|GENE= POL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id= Human immunodeficiency virus type 1 (isolate HXB2)])
}}
 
'''HIV-1 REVERSE TRANSCRIPTASE COMPLEXED WITH UC38'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1RT6 is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_type_1_(isolate_hxb2) Human immunodeficiency virus type 1 (isolate hxb2)] with <scene name='pdbligand=PO4:'>PO4</scene> and <scene name='pdbligand=UC3:'>UC3</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/RNA-directed_DNA_polymerase RNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.49 2.7.7.49] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RT6 OCA].  
1RT6 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_type_1_(isolate_hxb2) Human immunodeficiency virus type 1 (isolate hxb2)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RT6 OCA].  


==Reference==
==Reference==
Crystal structures of HIV-1 reverse transcriptase in complex with carboxanilide derivatives., Ren J, Esnouf RM, Hopkins AL, Warren J, Balzarini J, Stuart DI, Stammers DK, Biochemistry. 1998 Oct 13;37(41):14394-403. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9772165 9772165]
Crystal structures of HIV-1 reverse transcriptase in complex with carboxanilide derivatives., Ren J, Esnouf RM, Hopkins AL, Warren J, Balzarini J, Stuart DI, Stammers DK, Biochemistry. 1998 Oct 13;37(41):14394-403. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9772165 9772165]
[[Category: Human immunodeficiency virus type 1 (isolate hxb2)]]
[[Category: Human immunodeficiency virus type 1 (isolate hxb2)]]
[[Category: Protein complex]]
[[Category: Protein complex]]
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[[Category: PO4]]
[[Category: PO4]]
[[Category: UC3]]
[[Category: UC3]]
[[Category: aids]]
[[Category: aid]]
[[Category: drug design]]
[[Category: drug design]]
[[Category: hiv-1 reverse transcriptase]]
[[Category: hiv-1 reverse transcriptase]]
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[[Category: nucleotidyltransferase]]
[[Category: nucleotidyltransferase]]


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