1k4w: Difference between revisions
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{{STRUCTURE_1k4w| PDB=1k4w | SCENE= }} | {{STRUCTURE_1k4w| PDB=1k4w | SCENE= }} | ||
===X-ray structure of the orphan nuclear receptor ROR beta ligand-binding domain in the active conformation=== | ===X-ray structure of the orphan nuclear receptor ROR beta ligand-binding domain in the active conformation=== | ||
{{ABSTRACT_PUBMED_11689423}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/RORB_RAT RORB_RAT]] Orphan nuclear receptor required for normal postnatal development of rod and cone photoreceptor cells. Regulates transcription of OPN1SW in cone photoreceptor cells by binding the sequence 5'-AGGTCA-3' in the OPN1SW promoter. | |||
==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
<ref group="xtra">PMID:011689423</ref><references group="xtra"/> | <ref group="xtra">PMID:011689423</ref><references group="xtra"/><references/> | ||
[[Category: Rattus norvegicus]] | [[Category: Rattus norvegicus]] | ||
[[Category: Greiner, E.]] | [[Category: Greiner, E.]] | ||
Revision as of 18:53, 24 March 2013
X-ray structure of the orphan nuclear receptor ROR beta ligand-binding domain in the active conformation
Template:ABSTRACT PUBMED 11689423
Function
[RORB_RAT] Orphan nuclear receptor required for normal postnatal development of rod and cone photoreceptor cells. Regulates transcription of OPN1SW in cone photoreceptor cells by binding the sequence 5'-AGGTCA-3' in the OPN1SW promoter.
About this Structure
1k4w is a 2 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.
Reference
- Stehlin C, Wurtz JM, Steinmetz A, Greiner E, Schule R, Moras D, Renaud JP. X-ray structure of the orphan nuclear receptor RORbeta ligand-binding domain in the active conformation. EMBO J. 2001 Nov 1;20(21):5822-31. PMID:11689423 doi:10.1093/emboj/20.21.5822
