1nq3: Difference between revisions

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[[Image:1nq3.png|left|200px]]
==Crystal structure of the mammalian tumor associated antigen UK114==
<StructureSection load='1nq3' size='340' side='right' caption='[[1nq3]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1nq3]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Capra_hircus Capra hircus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NQ3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1NQ3 FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1qd9|1qd9]], [[1qu9|1qu9]], [[1jd1|1jd1]], [[1j7h|1j7h]]</td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1nq3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nq3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1nq3 RCSB], [http://www.ebi.ac.uk/pdbsum/1nq3 PDBsum]</span></td></tr>
<table>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nq/1nq3_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
The tumour-associated antigen UK114, isolated from goat liver, belongs to the YER057c/YIL051c/YjgF protein family, which has members in both the prokaryotes and eukaryotes. The crystal structure of a mammalian representative, goat UK114, was determined, revealing a trimeric arrangement in the crystal. It was confirmed by ultracentrifugation that UK114 is a trimer in solution. These results are in agreement with the published structures of homologues from unicellular organisms, but contrast with those reported for the rat homologue of UK114, for which a dimeric quaternary structure was proposed.


{{STRUCTURE_1nq3|  PDB=1nq3  |  SCENE=  }}
Structure and oligomeric state of the mammalian tumour-associated antigen UK114.,Deriu D, Briand C, Mistiniene E, Naktinis V, Grutter MG Acta Crystallogr D Biol Crystallogr. 2003 Sep;59(Pt 9):1676-8. Epub 2003, Aug 19. PMID:12925811<ref>PMID:12925811</ref>


===Crystal structure of the mammalian tumor associated antigen UK114===
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
 
</div>
{{ABSTRACT_PUBMED_12925811}}
== References ==
 
<references/>
==About this Structure==
__TOC__
[[1nq3]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Capra_hircus Capra hircus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NQ3 OCA].
</StructureSection>
 
==Reference==
<ref group="xtra">PMID:012925811</ref><references group="xtra"/>
[[Category: Capra hircus]]
[[Category: Capra hircus]]
[[Category: Briand, C.]]
[[Category: Briand, C.]]
Retrieved from "https://proteopedia.org/1nq3"