1rvu: Difference between revisions

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[[Image:1rvu.jpg|left|200px]]<br /><applet load="1rvu" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1rvu.jpg|left|200px]]
caption="1rvu, resolution 2.50&Aring;" />
 
'''E75Q MUTANT OF RABBIT CYTOSOLIC SERINE HYDROXYMETHYLTRANSFERASE'''<br />
{{Structure
|PDB= 1rvu |SIZE=350|CAPTION= <scene name='initialview01'>1rvu</scene>, resolution 2.50&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene> and <scene name='pdbligand=PLP:PYRIDOXAL-5'-PHOSPHATE'>PLP</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Glycine_hydroxymethyltransferase Glycine hydroxymethyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.2.1 2.1.2.1]
|GENE= SHMT1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9986 Oryctolagus cuniculus])
}}
 
'''E75Q MUTANT OF RABBIT CYTOSOLIC SERINE HYDROXYMETHYLTRANSFERASE'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1RVU is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus] with <scene name='pdbligand=PO4:'>PO4</scene> and <scene name='pdbligand=PLP:'>PLP</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Glycine_hydroxymethyltransferase Glycine hydroxymethyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.2.1 2.1.2.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RVU OCA].  
1RVU is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RVU OCA].  


==Reference==
==Reference==
Serine hydroxymethyltransferase: role of glu75 and evidence that serine is cleaved by a retroaldol mechanism., Szebenyi DM, Musayev FN, di Salvo ML, Safo MK, Schirch V, Biochemistry. 2004 Jun 8;43(22):6865-76. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15170323 15170323]
Serine hydroxymethyltransferase: role of glu75 and evidence that serine is cleaved by a retroaldol mechanism., Szebenyi DM, Musayev FN, di Salvo ML, Safo MK, Schirch V, Biochemistry. 2004 Jun 8;43(22):6865-76. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15170323 15170323]
[[Category: Glycine hydroxymethyltransferase]]
[[Category: Glycine hydroxymethyltransferase]]
[[Category: Oryctolagus cuniculus]]
[[Category: Oryctolagus cuniculus]]
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[[Category: one carbon metabolism]]
[[Category: one carbon metabolism]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:55:03 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 13:56:51 2008''