1rxc: Difference between revisions

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[[Image:1rxc.gif|left|200px]]<br /><applet load="1rxc" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1rxc.gif|left|200px]]
caption="1rxc, resolution 2.35&Aring;" />
 
'''E. COLI uridine phosphorylase: 5-fluorouracil ribose-1-phosphate complex'''<br />
{{Structure
|PDB= 1rxc |SIZE=350|CAPTION= <scene name='initialview01'>1rxc</scene>, resolution 2.35&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=R1P:RIBOSE-1-PHOSPHATE'>R1P</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=URF:5-FLUOROURACIL'>URF</scene> and <scene name='pdbligand=5UD:5-FLUOROURIDINE'>5UD</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Uridine_phosphorylase Uridine phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.3 2.4.2.3]
|GENE= UDP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
}}
 
'''E. COLI uridine phosphorylase: 5-fluorouracil ribose-1-phosphate complex'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1RXC is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=R1P:'>R1P</scene>, <scene name='pdbligand=PO4:'>PO4</scene>, <scene name='pdbligand=K:'>K</scene>, <scene name='pdbligand=URF:'>URF</scene> and <scene name='pdbligand=5UD:'>5UD</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Uridine_phosphorylase Uridine phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.3 2.4.2.3] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RXC OCA].  
1RXC is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RXC OCA].  


==Reference==
==Reference==
Crystal structures of Escherichia coli uridine phosphorylase in two native and three complexed forms reveal basis of substrate specificity, induced conformational changes and influence of potassium., Caradoc-Davies TT, Cutfield SM, Lamont IL, Cutfield JF, J Mol Biol. 2004 Mar 19;337(2):337-54. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15003451 15003451]
Crystal structures of Escherichia coli uridine phosphorylase in two native and three complexed forms reveal basis of substrate specificity, induced conformational changes and influence of potassium., Caradoc-Davies TT, Cutfield SM, Lamont IL, Cutfield JF, J Mol Biol. 2004 Mar 19;337(2):337-54. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15003451 15003451]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: uridine phosphorylase]]
[[Category: uridine phosphorylase]]


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