1s19: Difference between revisions

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[[Image:1s19.gif|left|200px]]<br /><applet load="1s19" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1s19.gif|left|200px]]
caption="1s19, resolution 2.1&Aring;" />
 
'''Crystal structure of VDR ligand binding domain complexed to calcipotriol.'''<br />
{{Structure
|PDB= 1s19 |SIZE=350|CAPTION= <scene name='initialview01'>1s19</scene>, resolution 2.1&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=MC9:CALCIPOTRIOL'>MC9</scene>
|ACTIVITY=
|GENE= VDR, NR1I1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Crystal structure of VDR ligand binding domain complexed to calcipotriol.'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1S19 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=MC9:'>MC9</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S19 OCA].  
1S19 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S19 OCA].  


==Reference==
==Reference==
Crystal structures of the vitamin D nuclear receptor liganded with the vitamin D side chain analogues calcipotriol and seocalcitol, receptor agonists of clinical importance. Insights into a structural basis for the switching of calcipotriol to a receptor antagonist by further side chain modification., Tocchini-Valentini G, Rochel N, Wurtz JM, Moras D, J Med Chem. 2004 Apr 8;47(8):1956-61. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15055995 15055995]
Crystal structures of the vitamin D nuclear receptor liganded with the vitamin D side chain analogues calcipotriol and seocalcitol, receptor agonists of clinical importance. Insights into a structural basis for the switching of calcipotriol to a receptor antagonist by further side chain modification., Tocchini-Valentini G, Rochel N, Wurtz JM, Moras D, J Med Chem. 2004 Apr 8;47(8):1956-61. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15055995 15055995]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: transcription regulation]]
[[Category: transcription regulation]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:56:49 2008''
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