1s5f: Difference between revisions

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[[Image:1s5f.jpg|left|200px]]<br /><applet load="1s5f" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1s5f.jpg|left|200px]]
caption="1s5f, resolution 2.60&Aring;" />
 
'''Cholera holotoxin, Crystal form 2'''<br />
{{Structure
|PDB= 1s5f |SIZE=350|CAPTION= <scene name='initialview01'>1s5f</scene>, resolution 2.60&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene> and <scene name='pdbligand=NA:SODIUM ION'>NA</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/NAD(+)--diphthamide_ADP-ribosyltransferase NAD(+)--diphthamide ADP-ribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.36 2.4.2.36]
|GENE= CTXA, TOXA, VC1457 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=666 Vibrio cholerae]), CTXB, TOXB, VC1456 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=666 Vibrio cholerae])
}}
 
'''Cholera holotoxin, Crystal form 2'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1S5F is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Vibrio_cholerae Vibrio cholerae] with <scene name='pdbligand=GAL:'>GAL</scene> and <scene name='pdbligand=NA:'>NA</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/NAD(+)--diphthamide_ADP-ribosyltransferase NAD(+)--diphthamide ADP-ribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.36 2.4.2.36] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S5F OCA].  
1S5F is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Vibrio_cholerae Vibrio cholerae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S5F OCA].  


==Reference==
==Reference==
Crystal structures of an intrinsically active cholera toxin mutant yield insight into the toxin activation mechanism., O'Neal CJ, Amaya EI, Jobling MG, Holmes RK, Hol WG, Biochemistry. 2004 Apr 6;43(13):3772-82. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15049684 15049684]
Crystal structures of an intrinsically active cholera toxin mutant yield insight into the toxin activation mechanism., O'Neal CJ, Amaya EI, Jobling MG, Holmes RK, Hol WG, Biochemistry. 2004 Apr 6;43(13):3772-82. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15049684 15049684]
[[Category: NAD(+)--diphthamide ADP-ribosyltransferase]]
[[Category: NAD(+)--diphthamide ADP-ribosyltransferase]]
[[Category: Protein complex]]
[[Category: Protein complex]]
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[[Category: GAL]]
[[Category: GAL]]
[[Category: NA]]
[[Category: NA]]
[[Category: ab5 toxins]]
[[Category: ab5 toxin]]
[[Category: adp ribose transferases]]
[[Category: adp ribose transferase]]
[[Category: cholera toxin]]
[[Category: cholera toxin]]
[[Category: heat-labile enterotoxin]]
[[Category: heat-labile enterotoxin]]


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