2m10: Difference between revisions
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{{STRUCTURE_2m10| PDB=2m10 | SCENE= }} | |||
===trans form of a photoswitchable PDZ domain crosslinked with an azobenzene derivative=== | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/PTN13_HUMAN PTN13_HUMAN]] Tyrosine phosphatase which regulates negatively FAS-induced apoptosis and NGFR-mediated pro-apoptotic signaling.<ref>PMID:15611135</ref> | |||
==About this Structure== | |||
[[2m10]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M10 OCA]. | |||
==Reference== | |||
<references group="xtra"/><references/> | |||
[[Category: Homo sapiens]] | |||
[[Category: Protein-tyrosine-phosphatase]] | |||
[[Category: Walser, R.]] | |||
[[Category: Hydrolase]] | |||
[[Category: Photoswitch]] | |||
Revision as of 14:11, 3 July 2013
trans form of a photoswitchable PDZ domain crosslinked with an azobenzene derivative
Function
[PTN13_HUMAN] Tyrosine phosphatase which regulates negatively FAS-induced apoptosis and NGFR-mediated pro-apoptotic signaling.[1]
About this Structure
2m10 is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA.
Reference
- ↑ Villa F, Deak M, Bloomberg GB, Alessi DR, van Aalten DM. Crystal structure of the PTPL1/FAP-1 human tyrosine phosphatase mutated in colorectal cancer: evidence for a second phosphotyrosine substrate recognition pocket. J Biol Chem. 2005 Mar 4;280(9):8180-7. Epub 2004 Dec 20. PMID:15611135 doi:10.1074/jbc.M412211200
