3zeh: Difference between revisions

Line 1:

~~'''Unreleased~~ structure~~'''~~

===Solution structure of the Hs. PSIP1 PWWP domain===

The ~~entry 3zeh~~ is ~~ON HOLD until Paper Publication~~

==Disease==

[[http://www.uniprot.org/uniprot/PSIP1_HUMAN PSIP1_HUMAN]] Note=A chromosomal aberration involving PSIP1 is associated with pediatric acute myeloid leukemia (AML) with intermediate characteristics between M2-M3 French-American-British (FAB) subtypes. Translocation t(9;11)(p22;p15) with NUP98. The chimeric transcript is an in-frame fusion of NUP98 exon 8 to PSIP1/LEDGF exon 4.

~~Authors~~: ~~van Ingen, H~~.~~, van Nuland, R~~.~~, Timmers, H~~.T.M.~~, Boelens, R~~.

==Function==

[[http://www.uniprot.org/uniprot/PSIP1_HUMAN PSIP1_HUMAN]] Transcriptional coactivator involved in neuroepithelial stem cell differentiation and neurogenesis. Involved in particular in lens epithelial cell gene regulation and stress responses. May play an important role in lens epithelial to fiber cell terminal differentiation. May play a protective role during stress-induced apoptosis. Isoform 2 is a more general and stronger transcriptional coactivator. Isoform 2 may also act as an adapter to coordinate pre-mRNA splicing. Cellular cofactor for lentiviral integration.<ref>PMID:15642333</ref>

~~Description~~: ~~Solution structure of the Hs~~. ~~PSIP1 PWWP domain~~

==About this Structure==

[[3zeh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZEH OCA].

==Reference==

[[Category: Homo sapiens]]

[[Category: Boelens, R.]]

[[Category: Ingen, H van.]]

[[Category: Nuland, R van.]]

[[Category: Timmers, H T.M.]]

[[Category: Dna binding]]

Navigation menu

Page actions

Page actions

Personal tools

Navigation

Search

Tools

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+{{STRUCTURE_3zeh|  PDB=3zeh  |  SCENE=  }}
+===Solution structure of the Hs. PSIP1 PWWP domain===
+{{ABSTRACT_PUBMED_23656834}}
-The entry 3zeh is ON HOLD  until Paper Publication
+==Disease==
+[[http://www.uniprot.org/uniprot/PSIP1_HUMAN PSIP1_HUMAN]] Note=A chromosomal aberration involving PSIP1 is associated with pediatric acute myeloid leukemia (AML) with intermediate characteristics between M2-M3 French-American-British (FAB) subtypes. Translocation t(9;11)(p22;p15) with NUP98. The chimeric transcript is an in-frame fusion of NUP98 exon 8 to PSIP1/LEDGF exon 4.
-Authors: van Ingen, H., van Nuland, R., Timmers, H.T.M., Boelens, R.
+==Function==
+[[http://www.uniprot.org/uniprot/PSIP1_HUMAN PSIP1_HUMAN]] Transcriptional coactivator involved in neuroepithelial stem cell differentiation and neurogenesis. Involved in particular in lens epithelial cell gene regulation and stress responses. May play an important role in lens epithelial to fiber cell terminal differentiation. May play a protective role during stress-induced apoptosis. Isoform 2 is a more general and stronger transcriptional coactivator. Isoform 2 may also act as an adapter to coordinate pre-mRNA splicing. Cellular cofactor for lentiviral integration.<ref>PMID:15642333</ref>
-Description: Solution structure of the Hs. PSIP1 PWWP domain
+==About this Structure==
+[[3zeh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZEH OCA].
+==Reference==
+<ref group="xtra">PMID:023656834</ref><references group="xtra"/><references/>
+[[Category: Homo sapiens]]
+[[Category: Boelens, R.]]
+[[Category: Ingen, H van.]]
+[[Category: Nuland, R van.]]
+[[Category: Timmers, H T.M.]]
+[[Category: Dna binding]]