4hxo: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

===Brd4 Bromodomain 1 complex with 3-{[(3-METHYL-1,2-OXAZOL-5-YL)METHYL]SULFANYL}[1,2,4]TRIAZOLO[4,3-A]PYRIDINE inhibitor===

~~The entry 4hxo~~ is ~~ON HOLD~~ ~~until Paper Publication~~

==Disease==

[[http://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Note=A chromosomal aberration involving BRD4 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;19)(q14;p13) with NUT which produces a BRD4-NUT fusion protein.<ref>PMID:12543779</ref> <ref>PMID:11733348</ref>

~~Authors~~: ~~Xiong, B~~.~~, Cao, D~~.~~Y., Chen, W.Y., Chen, T.T., Xu, Y.C., Shen, J.K~~.

==Function==

[[http://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Plays a role in a process governing chromosomal dynamics during mitosis (By similarity).

~~Description~~: Brd4 Bromodomain 1 complex ~~with its novel inhibitors~~

==About this Structure==

[[4hxo]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HXO OCA].

==Reference==

[[Category: Homo sapiens]]

[[Category: Cao, D Y.]]

[[Category: Chen, T T.]]

[[Category: Chen, W Y.]]

[[Category: Shen, J K.]]

[[Category: Xiong, B.]]

[[Category: Xu, Y C.]]

[[Category: Brd4]]

[[Category: Bromodomain]]

[[Category: Four alpha helice]]

[[Category: Protein binding-inhibitor complex]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+{{STRUCTURE_4hxo|  PDB=4hxo  |  SCENE=  }}
+===Brd4 Bromodomain 1 complex with 3-{[(3-METHYL-1,2-OXAZOL-5-YL)METHYL]SULFANYL}[1,2,4]TRIAZOLO[4,3-A]PYRIDINE inhibitor===
+{{ABSTRACT_PUBMED_23530754}}
-The entry 4hxo is ON HOLD  until Paper Publication
+==Disease==
+[[http://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Note=A chromosomal aberration involving BRD4 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;19)(q14;p13) with NUT which produces a BRD4-NUT fusion protein.<ref>PMID:12543779</ref> <ref>PMID:11733348</ref>
-Authors: Xiong, B., Cao, D.Y., Chen, W.Y., Chen, T.T., Xu, Y.C., Shen, J.K.
+==Function==
+[[http://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Plays a role in a process governing chromosomal dynamics during mitosis (By similarity).
-Description: Brd4 Bromodomain 1 complex with its novel inhibitors
+==About this Structure==
+[[4hxo]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HXO OCA].
+==Reference==
+<references group="xtra"/><references/>
+[[Category: Homo sapiens]]
+[[Category: Cao, D Y.]]
+[[Category: Chen, T T.]]
+[[Category: Chen, W Y.]]
+[[Category: Shen, J K.]]
+[[Category: Xiong, B.]]
+[[Category: Xu, Y C.]]
+[[Category: Brd4]]
+[[Category: Bromodomain]]
+[[Category: Four alpha helice]]
+[[Category: Protein binding-inhibitor complex]]