2lkq: Difference between revisions
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{{STRUCTURE_2lkq| PDB=2lkq | SCENE= }} | {{STRUCTURE_2lkq| PDB=2lkq | SCENE= }} | ||
===NMR structure of the lambda 5 22-45 peptide=== | |||
{{ABSTRACT_PUBMED_23124203}} | |||
=== | ==Disease== | ||
[[http://www.uniprot.org/uniprot/IGLL1_HUMAN IGLL1_HUMAN]] Defects in IGLL1 are the cause of agammaglobulinemia type 2 (AGM2) [MIM:[http://omim.org/entry/613500 613500]]. It is a primary immunodeficiency characterized by profoundly low or absent serum antibodies and low or absent circulating B-cells due to an early block of B-cell development. Affected individuals develop severe infections in the first years of life. | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/IGLL1_HUMAN IGLL1_HUMAN]] Critical for B-cell development.<ref>PMID:9419212</ref> | |||
==About this Structure== | ==About this Structure== | ||
[[2lkq]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LKQ OCA]. | [[2lkq]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LKQ OCA]. | ||
==Reference== | |||
<references group="xtra"/><references/> | |||
[[Category: Boned, A.]] | [[Category: Boned, A.]] | ||
[[Category: Bornet, O.]] | [[Category: Bornet, O.]] | ||
