1sep: Difference between revisions

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[[Image:1sep.jpg|left|200px]]<br /><applet load="1sep" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1sep.jpg|left|200px]]
caption="1sep, resolution 1.95&Aring;" />
 
'''MOUSE SEPIAPTERIN REDUCTASE COMPLEXED WITH NADP AND SEPIAPTERIN'''<br />
{{Structure
|PDB= 1sep |SIZE=350|CAPTION= <scene name='initialview01'>1sep</scene>, resolution 1.95&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene> and <scene name='pdbligand=BIO:BIOPTERIN'>BIO</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Sepiapterin_reductase Sepiapterin reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.153 1.1.1.153]
|GENE=
}}
 
'''MOUSE SEPIAPTERIN REDUCTASE COMPLEXED WITH NADP AND SEPIAPTERIN'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1SEP is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] with <scene name='pdbligand=NAP:'>NAP</scene> and <scene name='pdbligand=BIO:'>BIO</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Sepiapterin_reductase Sepiapterin reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.153 1.1.1.153] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SEP OCA].  
1SEP is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SEP OCA].  


==Reference==
==Reference==
The 1.25 A crystal structure of sepiapterin reductase reveals its binding mode to pterins and brain neurotransmitters., Auerbach G, Herrmann A, Gutlich M, Fischer M, Jacob U, Bacher A, Huber R, EMBO J. 1997 Dec 15;16(24):7219-30. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9405351 9405351]
The 1.25 A crystal structure of sepiapterin reductase reveals its binding mode to pterins and brain neurotransmitters., Auerbach G, Herrmann A, Gutlich M, Fischer M, Jacob U, Bacher A, Huber R, EMBO J. 1997 Dec 15;16(24):7219-30. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9405351 9405351]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Sepiapterin reductase]]
[[Category: Sepiapterin reductase]]
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[[Category: tetrahydrobiopterin]]
[[Category: tetrahydrobiopterin]]


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