4i0o: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4i0o|  PDB=4i0o  |  SCENE=  }}
===Nucleoporin ELYS (aa1-494), Mus musculus===
{{ABSTRACT_PUBMED_23499022}}


The entry 4i0o is ON HOLD until Paper Publication
==Function==
[[http://www.uniprot.org/uniprot/ELYS_MOUSE ELYS_MOUSE]] Required for the assembly of a functional nuclear pore complex (NPC) on the surface of chromosomes as nuclei form at the end of mitosis. May initiate NPC assembly by binding to chromatin and recruiting the Nup107-160 subcomplex of the NPC. Also required for the localization of the Nup107-160 subcomplex of the NPC to the kinetochore during mitosis and for the completion of cytokinesis (By similarity). Has also been proposed to function as a transcription factor which may play a specific role in hematopoietic tissues (PubMed:11952839).<ref>PMID:11952839</ref>  


Authors: Bilokapic, S.
==About this Structure==
[[4i0o]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I0O OCA].  


Description: Structure of the WD repeat-containing protein
==Reference==
<references group="xtra"/><references/>
[[Category: Mus musculus]]
[[Category: Bilokapic, S.]]
[[Category: Schwartz, T U.]]
[[Category: Beta propeller]]
[[Category: Mrna transport]]
[[Category: Nuclear pore complex]]
[[Category: Structural protein]]
[[Category: Wd40 repeat]]

Revision as of 20:28, 17 April 2013

Template:STRUCTURE 4i0o

Nucleoporin ELYS (aa1-494), Mus musculus

Template:ABSTRACT PUBMED 23499022

Function

[ELYS_MOUSE] Required for the assembly of a functional nuclear pore complex (NPC) on the surface of chromosomes as nuclei form at the end of mitosis. May initiate NPC assembly by binding to chromatin and recruiting the Nup107-160 subcomplex of the NPC. Also required for the localization of the Nup107-160 subcomplex of the NPC to the kinetochore during mitosis and for the completion of cytokinesis (By similarity). Has also been proposed to function as a transcription factor which may play a specific role in hematopoietic tissues (PubMed:11952839).[1]

About this Structure

4i0o is a 1 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.

Reference

  1. ↑ Kimura N, Takizawa M, Okita K, Natori O, Igarashi K, Ueno M, Nakashima K, Nobuhisa I, Taga T. Identification of a novel transcription factor, ELYS, expressed predominantly in mouse foetal haematopoietic tissues. Genes Cells. 2002 Apr;7(4):435-46. PMID:11952839

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