1svs: Difference between revisions

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[[Image:1svs.jpg|left|200px]]<br /><applet load="1svs" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1svs.jpg|left|200px]]
caption="1svs, resolution 1.5&Aring;" />
 
'''Structure of the K180P mutant of Gi alpha subunit bound to GppNHp.'''<br />
{{Structure
|PDB= 1svs |SIZE=350|CAPTION= <scene name='initialview01'>1svs</scene>, resolution 1.5&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene> and <scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER'>GNP</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Heterotrimeric_G-protein_GTPase Heterotrimeric G-protein GTPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.5.1 3.6.5.1]
|GENE= GNAI1, GNAI-1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Rattus norvegicus])
}}
 
'''Structure of the K180P mutant of Gi alpha subunit bound to GppNHp.'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1SVS is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus] with <scene name='pdbligand=MG:'>MG</scene> and <scene name='pdbligand=GNP:'>GNP</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Heterotrimeric_G-protein_GTPase Heterotrimeric G-protein GTPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.5.1 3.6.5.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SVS OCA].  
1SVS is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SVS OCA].  


==Reference==
==Reference==
Uncoupling conformational change from GTP hydrolysis in a heterotrimeric G protein alpha-subunit., Thomas CJ, Du X, Li P, Wang Y, Ross EM, Sprang SR, Proc Natl Acad Sci U S A. 2004 May 18;101(20):7560-5. Epub 2004 May 5. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15128951 15128951]
Uncoupling conformational change from GTP hydrolysis in a heterotrimeric G protein alpha-subunit., Thomas CJ, Du X, Li P, Wang Y, Ross EM, Sprang SR, Proc Natl Acad Sci U S A. 2004 May 18;101(20):7560-5. Epub 2004 May 5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15128951 15128951]
[[Category: Heterotrimeric G-protein GTPase]]
[[Category: Heterotrimeric G-protein GTPase]]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
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[[Category: k180p mutation]]
[[Category: k180p mutation]]


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