Sandbox Reserved 717: Difference between revisions

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== '''Adsorption and penetration phases''' ==

[[Image:chgm form.jpg|300px|thumb|right|Deployement of short tails]]

First, the viral particles recognize and bind reversibly to the outer membrane protein C (OmpC) or the cell-surface lipopolysaccharide receptors thanks to six long tail fibers which are connected to the baseplate. After at least three long tail fibers have bound, the baseplate conformation changes: from a hexagon shape, it becomes a six-pointed star. This change can be the result of changing the interactions between proteins.

First, the viral particles recognize and bind reversibly to the outer membrane protein C (OmpC) or the cell-surface lipopolysaccharide receptors thanks to six long tail fibers which are connected to the baseplate. After at least three long tail fibers have bound, the baseplate conformation changes: from a hexagon shape, it becomes a six-pointed star. This change can be the result of changing the interactions between proteins. It has two consequences.

~~It has two consequences.~~ The first one is the unfolding of the short tail fibers, which are under the baseplate. Thus, they are able to attach irreversibly to the host cell surface. The second one is the induction of the tail sheath’s contraction. Afterwards the tail tube is driving through the cell membrane. The activated lysozyme domain of gp5 degraded the peptidoglycan layer. To finish, the phage DNA single-stranded is injected into the bacterial cytoplasm through the tail tube.

The first one is the unfolding of the short tail fibers, which are under the baseplate. Thus, they are able to attach irreversibly to the host cell surface.

The second one is the induction of the tail sheath’s contraction. Afterwards the tail tube is driving through the cell membrane. The activated lysozyme domain of gp5 degraded the peptidoglycan layer.

To finish, the phage DNA single-stranded is injected into the bacterial cytoplasm through the tail tube.

== '''Role of gp12''' ==

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@@ Line 23: / Line 23: @@
 == '''Adsorption and penetration phases''' ==
 [[Image:chgm form.jpg|300px|thumb|right|Deployement of short tails]]
-First, the viral particles recognize and bind reversibly to the outer membrane protein C (OmpC) or the cell-surface lipopolysaccharide receptors thanks to six long tail fibers which are connected to the baseplate. After at least three long tail fibers have bound, the baseplate conformation changes: from a hexagon shape, it becomes a six-pointed star. This change can be the result of changing the interactions between proteins.
+First, the viral particles recognize and bind reversibly to the outer membrane protein C (OmpC) or the cell-surface lipopolysaccharide receptors thanks to six long tail fibers which are connected to the baseplate. After at least three long tail fibers have bound, the baseplate conformation changes: from a hexagon shape, it becomes a six-pointed star. This change can be the result of changing the interactions between proteins. It has two consequences.
-It has two consequences. The first one is the unfolding of the short tail fibers, which are under the baseplate. Thus, they are able to attach irreversibly to the host cell surface. The second one is the induction of the tail sheath’s contraction. Afterwards the tail tube is driving through the cell membrane. The activated lysozyme domain of gp5 degraded the peptidoglycan layer. To finish, the phage DNA single-stranded is injected into the bacterial cytoplasm through the tail tube.
+The first one is the unfolding of the short tail fibers, which are under the baseplate. Thus, they are able to attach irreversibly to the host cell surface.
+The second one is the induction of the tail sheath’s contraction. Afterwards the tail tube is driving through the cell membrane. The activated lysozyme domain of gp5 degraded the peptidoglycan layer.
+To finish, the phage DNA single-stranded is injected into the bacterial cytoplasm through the tail tube.
 == '''Role of gp12''' ==