Sandbox Reserved 704: Difference between revisions
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The translocation between these two states seems to be allowed thanks to the flexibility of the CCA end. It is able to go towards either the aminoacylation site either the editing site whereas the rest of the tRNA remains bound to the enzyme core. These two conformation states involved two modes of A73 recognition and also of C74, C75 and A73, residues of the 3’-terminal region. | The translocation between these two states seems to be allowed thanks to the flexibility of the CCA end. It is able to go towards either the aminoacylation site either the editing site whereas the rest of the tRNA remains bound to the enzyme core. These two conformation states involved two modes of A73 recognition and also of C74, C75 and A73, residues of the 3’-terminal region. | ||
{| class="wikitable centre" | |||
| ... | |||
| The editing complex || The aminoacylation complex | |||
|- | |||
| Conformation mode || A73 and C74 stack together | |||
| A73 and C74 are perpendicular to each other | |||
|- | |||
| Recognitions mode A73 || Hydrogen bond between N1 of A73 and NH of Asp504 in the main chain | |||
| Hydrogen bond between N6-H2 of A73 and CO of Lys 505 in the main chain | |||
Hydrogen bond between N1 of A73 and NH of Asp504 | |||
|- | |||
|Cellule 4.1 || Cellule 4.2 | |||
| Cellule 4.3 | |||
|} | |||
== References == | == References == | ||
<references/> | <references/> | ||
