Sandbox Reserved 717: Difference between revisions

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Basic putative binding residues:
Basic putative binding residues:
Lys446, Lys422, Arg504, Arg424,Arg513
Lys446, Lys422, Arg504, Arg424, Arg513


Aromatic putative binding residues:
Aromatic putative binding residues:
Tyr454, Phe451, Trp477, Phe468, Phe460, Phe420, Tyr488, Tyr444, His408, Tyr433
Tyr454, Phe451, Trp477, Phe468, Phe460, Phe420, Tyr488, Tyr444, His408, Tyr433
'''It can not be ruled out that also other amino acids are important for binding! Further it can not be ruled out that not all of these named amino acids are important for binding'''
The mentioned amino acids are starting point for site-directed mutations and /or other biochemical experiments to clarify the location of this binding site.