Sandbox Reserved 717: Difference between revisions
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== '''Description of Bacteriophage T4''' == | == '''Description of Bacteriophage T4''' == | ||
[[Image:T4_schema.jpg|thumb|left|Schematic representation of bacteriophage T4 <ref>doi:10.1186/1743-422X-7-355</ref>]] | [[Image:T4_schema.jpg|thumb|left|Schematic representation of bacteriophage T4 <ref name=r1>doi:10.1186/1743-422X-7-355</ref>]] | ||
Bacteriophage T4 belongs to the Myoviridae family and the Caudovirales order. It belongs to this order and family because of its complex tail structure. In this complex tail structures many proteins are involved. It infects Escherichia coli bacteria. | Bacteriophage T4 belongs to the Myoviridae family and the Caudovirales order. It belongs to this order and family because of its complex tail structure. In this complex tail structures many proteins are involved. It infects Escherichia coli bacteria. | ||
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== '''Adsorption and penetration phases''' == | == '''Adsorption and penetration phases''' == | ||
[[Image:chgm form.jpg|300px|thumb|right|Deployement of short tails | [[Image:chgm form.jpg|300px|thumb|right|Deployement of short tails | ||
A: Hexagonal conformation, B: Star conformation gp12 in manganta and gp10 in yellow <ref>doi:10.1186/1743-422X-7-355</ref>]] | A: Hexagonal conformation, B: Star conformation gp12 in manganta and gp10 in yellow <ref name=r1>doi:10.1186/1743-422X-7-355</ref>]] | ||
First, the viral particles recognize and bind reversibly to the outer membrane protein C (OmpC) or the cell-surface lipopolysaccharide receptors thanks to six long tail fibers which are connected to the baseplate. After at least three long tail fibers have bound, the baseplate conformation changes: from a hexagon shape, it becomes a six-pointed star. This change can be the result of changing the interactions between proteins. It has two consequences. | First, the viral particles recognize and bind reversibly to the outer membrane protein C (OmpC) or the cell-surface lipopolysaccharide receptors thanks to six long tail fibers which are connected to the baseplate. After at least three long tail fibers have bound, the baseplate conformation changes: from a hexagon shape, it becomes a six-pointed star. This change can be the result of changing the interactions between proteins. It has two consequences. | ||
