Sandbox Reserved 717: Difference between revisions
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During the first step of the lytic cycle, the short tail fibers gp12 attach the virion to the host cell. | During the first step of the lytic cycle, the short tail fibers gp12 attach the virion to the host cell. | ||
Thanks to a three-dimensional cryoelectron microscopy, a reconstruction of the baseplate was determined to a resolution of 12 Angstrom. It has shown that the total length of the gp12 density is inferior at 340 Å. <ref>doi:10.1186/1743-422X-7-355</ref> | Thanks to a three-dimensional cryoelectron microscopy, a reconstruction of the baseplate was determined to a resolution of 12 Angstrom. It has shown that the total length of the gp12 density is inferior at 340 Å. <ref name=r1>doi:10.1186/1743-422X-7-355</ref> | ||
This technique was also a way to determine the interactions between the different proteins and their localization. Thus, interactions of the short tail fibers with each other and with the gp11 maintain the hexagon shape stability. The gp11 is also associated with gp10, which is clamped between the three fingers of gp11. This association between gp10 and gp11 is essential for the attachment of gp12 to the baseplate. When a rotation of gp11 around its three-fold axis occurs, the end of the short tail fiber is oriented toward the host cell surface. | This technique was also a way to determine the interactions between the different proteins and their localization. Thus, interactions of the short tail fibers with each other and with the gp11 maintain the hexagon shape stability. The gp11 is also associated with gp10, which is clamped between the three fingers of gp11. This association between gp10 and gp11 is essential for the attachment of gp12 to the baseplate. When a rotation of gp11 around its three-fold axis occurs, the end of the short tail fiber is oriented toward the host cell surface. | ||
