4hka: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4hka|  PDB=4hka  |  SCENE=  }}
===Crystal structure of Drosophila melanogaster tryptophan 2,3-dioxygenase in complex with HEME===
{{ABSTRACT_PUBMED_23333332}}


The entry 4hka is ON HOLD  until Paper Publication
==Function==
[[http://www.uniprot.org/uniprot/T23O_DROME T23O_DROME]] Catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring (By similarity). Required during larval growth to control the level of potentially harmful free tryptophan in the hemolymph. In the adult the same reaction is the first step in the ommochrome biosynthetic pathway.<ref>PMID:2108317</ref>


Authors: Huang, W., Ding, J.
==About this Structure==
[[4hka]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HKA OCA].  


Description: Crystal structure of Drosophila melanogaster tryptophan 2,3-dioxygenase in complex with HEME
==Reference==
<references group="xtra"/><references/>
[[Category: Drosophila melanogaster]]
[[Category: Tryptophan 2,3-dioxygenase]]
[[Category: Ding, J.]]
[[Category: Huang, W.]]
[[Category: Catalytic mechanism]]
[[Category: Kynurenine pathway]]
[[Category: Oxidoreductase]]
[[Category: Regulatory mechanism]]