1t9a: Difference between revisions

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[[Image:1t9a.gif|left|200px]]<br /><applet load="1t9a" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1t9a.gif|left|200px]]
caption="1t9a, resolution 2.59&Aring;" />
 
'''Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide, tribenuron methyl'''<br />
{{Structure
|PDB= 1t9a |SIZE=350|CAPTION= <scene name='initialview01'>1t9a</scene>, resolution 2.59&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=1TB:METHYL+2-[4-METHOXY-6-METHYL-1,3,5-TRAZIN-2-YL(METHYL)CARBAMOYLSULFAMOYL]BENZOATE'>1TB</scene>, <scene name='pdbligand=P23:PROPYL+TRIHYDROGEN+DIPHOSPHATE'>P23</scene>, <scene name='pdbligand=YF3:2-{[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]AMINO}PROPANE-1-THIOL'>YF3</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene> and <scene name='pdbligand=YF4:5-{[ETHYL(METHYL)AMINO]METHYL}-2-METHYL-5,6-DIHYDROPYRIMIDIN-4-AMINE'>YF4</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Acetolactate_synthase Acetolactate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.2.1.6 2.2.1.6]
|GENE= ILV2, SMR1, YMR108W, YM9718.07 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])
}}
 
'''Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide, tribenuron methyl'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1T9A is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae] with <scene name='pdbligand=K:'>K</scene>, <scene name='pdbligand=MG:'>MG</scene>, <scene name='pdbligand=1TB:'>1TB</scene>, <scene name='pdbligand=P23:'>P23</scene>, <scene name='pdbligand=YF3:'>YF3</scene>, <scene name='pdbligand=FAD:'>FAD</scene> and <scene name='pdbligand=YF4:'>YF4</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Acetolactate_synthase Acetolactate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.2.1.6 2.2.1.6] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T9A OCA].  
1T9A is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T9A OCA].  


==Reference==
==Reference==
Elucidating the specificity of binding of sulfonylurea herbicides to acetohydroxyacid synthase., McCourt JA, Pang SS, Guddat LW, Duggleby RG, Biochemistry. 2005 Feb 22;44(7):2330-8. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15709745 15709745]
Elucidating the specificity of binding of sulfonylurea herbicides to acetohydroxyacid synthase., McCourt JA, Pang SS, Guddat LW, Duggleby RG, Biochemistry. 2005 Feb 22;44(7):2330-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15709745 15709745]
[[Category: Acetolactate synthase]]
[[Category: Acetolactate synthase]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: tribenuron methyl]]
[[Category: tribenuron methyl]]


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