MECDP synthase: Difference between revisions

Revision as of 13:05, 2 January 2013 view source Michal Harel (talk \| contribs) 32,820 edits New page: '''MECDP synthase''' (MECPS) participates in mevalonate-independent steroid biosynthesis. It converts 2-phospho-4-(cytidine 5’-diphospho)-2-C-methyl-D-erythritol (2P-CDME) to 2-C-methy...		Revision as of 13:10, 2 January 2013 view source Michal Harel (talk \| contribs) 32,820 edits No edit summary Newer edit →
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			{{STRUCTURE_1gx1\| PDB=1gx1 \| SIZE=400\| SCENE= \|right\|CAPTION=MECDP synthase dimer complex with CDP, Mn++ and Zn+2 ion, [[1gx1]] }}

	'''MECDP synthase''' (MECPS) participates in mevalonate-independent steroid biosynthesis. It converts 2-phospho-4-(cytidine 5’-diphospho)-2-C-methyl-D-erythritol (2P-CDME) to 2-C-methyl-D-erythritol 2, 4-cyclodiphosphate (MECP) and CMP. MECPS contains metal binding sites which are required for catalysis. MECPS is a potential antimalarial drug target.		'''MECDP synthase''' (MECPS) participates in mevalonate-independent steroid biosynthesis. It converts 2-phospho-4-(cytidine 5’-diphospho)-2-C-methyl-D-erythritol (2P-CDME) to 2-C-methyl-D-erythritol 2, 4-cyclodiphosphate (MECP) and CMP. MECPS contains metal binding sites which are required for catalysis. MECPS is a potential antimalarial drug target.

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