Sandbox Reserved 717: Difference between revisions

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==='''The 33kDa Fragment''' <ref name=r3>PMID: 12888344</ref> <ref>PMID:11530935</ref> ===
==='''The 33kDa Fragment''' <ref name=r3>PMID: 12888344</ref> <ref>PMID:11530935</ref> ===
The 33kDa fragment (PDB:1H6W)  was generated in the presence of EDTA [3]. This fragment contains the residues <scene name='Sandbox_Reserved_717/Myfirstscene/1'>85-395</scene> and <scene name='Sandbox_Reserved_717/Mysecondscene/1'>518-527</scene> .  The residues 397-517 are lacking because of internal deletion.
The 33kDa fragment (PDB:1H6W)  was generated in the presence of EDTA <ref name=r3>PMID: 12888344</ref>. This fragment contains the residues <scene name='Sandbox_Reserved_717/Myfirstscene/1'>85-395</scene> and <scene name='Sandbox_Reserved_717/Mysecondscene/1'>518-527</scene> .  The residues 397-517 are lacking because of internal deletion.
The 33kDa fragment can be further sub-divided into two subunits <ref name=r3>PMID: 12888344</ref>. The <scene name='Sandbox_Reserved_717/Mythirdscene/1'>neck</scene>  (residue 333-341) and the collar (residues <scene name='Sandbox_Reserved_717/Mythirdscene/2'>342-396 </scene> plus <scene name='Sandbox_Reserved_717/Mythirdscene/3'> 518-527</scene>). The neck connects the body of the fibre to its C-terminal collar and receptor-binding site. It consists of a triple alpha-helix which is built by the residues 333-341.
The 33kDa fragment can be further sub-divided into two subunits <ref name=r3>PMID: 12888344</ref>. The <scene name='Sandbox_Reserved_717/Mythirdscene/1'>neck</scene>  (residue 333-341) and the collar (residues <scene name='Sandbox_Reserved_717/Mythirdscene/2'>342-396 </scene> plus <scene name='Sandbox_Reserved_717/Mythirdscene/3'> 518-527</scene>). The neck connects the body of the fibre to its C-terminal collar and receptor-binding site. It consists of a triple alpha-helix which is built by the residues 333-341.
The collar domain is a small globular domain. It contains six beta-strands and an alpha-helix <ref name=r3>PMID: 12888344</ref>.
The collar domain is a small globular domain. It contains six beta-strands and an alpha-helix <ref name=r3>PMID: 12888344</ref>.