1the: Difference between revisions

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[[Image:1the.gif|left|200px]]<br /><applet load="1the" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1the.gif|left|200px]]
caption="1the, resolution 1.9&Aring;" />
 
'''CRYSTAL STRUCTURES OF RECOMBINANT RAT CATHEPSIN B AND A CATHEPSIN B-INHIBITOR COMPLEX: IMPLICATIONS FOR STRUCTURE-BASED INHIBITOR DESIGN'''<br />
{{Structure
|PDB= 1the |SIZE=350|CAPTION= <scene name='initialview01'>1the</scene>, resolution 1.9&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=PHQ:FORMIC ACID BENZYL ESTER'>PHQ</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Cathepsin_B Cathepsin B], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.1 3.4.22.1]
|GENE= CDNA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Rattus norvegicus])
}}
 
'''CRYSTAL STRUCTURES OF RECOMBINANT RAT CATHEPSIN B AND A CATHEPSIN B-INHIBITOR COMPLEX: IMPLICATIONS FOR STRUCTURE-BASED INHIBITOR DESIGN'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1THE is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus] with <scene name='pdbligand=PHQ:'>PHQ</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Cathepsin_B Cathepsin B], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.1 3.4.22.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1THE OCA].  
1THE is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1THE OCA].  


==Reference==
==Reference==
Crystal structures of recombinant rat cathepsin B and a cathepsin B-inhibitor complex. Implications for structure-based inhibitor design., Jia Z, Hasnain S, Hirama T, Lee X, Mort JS, To R, Huber CP, J Biol Chem. 1995 Mar 10;270(10):5527-33. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=7890671 7890671]
Crystal structures of recombinant rat cathepsin B and a cathepsin B-inhibitor complex. Implications for structure-based inhibitor design., Jia Z, Hasnain S, Hirama T, Lee X, Mort JS, To R, Huber CP, J Biol Chem. 1995 Mar 10;270(10):5527-33. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7890671 7890671]
[[Category: Cathepsin B]]
[[Category: Cathepsin B]]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
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[[Category: thiol protease]]
[[Category: thiol protease]]


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