1thz: Difference between revisions

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[[Image:1thz.gif|left|200px]]<br /><applet load="1thz" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1thz.gif|left|200px]]
caption="1thz, resolution 1.80&Aring;" />
 
'''Crystal Structure of Avian AICAR Transformylase in Complex with a Novel Inhibitor Identified by Virtual Ligand Screening'''<br />
{{Structure
|PDB= 1thz |SIZE=350|CAPTION= <scene name='initialview01'>1thz</scene>, resolution 1.80&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=K:POTASSIUM+ION'>K</scene> and <scene name='pdbligand=326:2-{(E)-[5-HYDROXY-3-METHYL-1-(2-METHYL-4-SULFOPHENYL)-1H-PYRAZOL-4-YL]DIAZENYL}-4-SULFOBENZOIC ACID'>326</scene>
|ACTIVITY=
|GENE= ATIC, PURH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9031 Gallus gallus])
}}
 
'''Crystal Structure of Avian AICAR Transformylase in Complex with a Novel Inhibitor Identified by Virtual Ligand Screening'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1THZ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus] with <scene name='pdbligand=K:'>K</scene> and <scene name='pdbligand=326:'>326</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1THZ OCA].  
1THZ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1THZ OCA].  


==Reference==
==Reference==
Crystal structure of avian aminoimidazole-4-carboxamide ribonucleotide transformylase in complex with a novel non-folate inhibitor identified by virtual ligand screening., Xu L, Li C, Olson AJ, Wilson IA, J Biol Chem. 2004 Nov 26;279(48):50555-65. Epub 2004 Sep 7. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15355974 15355974]
Crystal structure of avian aminoimidazole-4-carboxamide ribonucleotide transformylase in complex with a novel non-folate inhibitor identified by virtual ligand screening., Xu L, Li C, Olson AJ, Wilson IA, J Biol Chem. 2004 Nov 26;279(48):50555-65. Epub 2004 Sep 7. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15355974 15355974]
[[Category: Gallus gallus]]
[[Category: Gallus gallus]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: virtual ligand screening]]
[[Category: virtual ligand screening]]


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