1soh: Difference between revisions
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{{STRUCTURE_1soh| PDB=1soh | SCENE= }} | {{STRUCTURE_1soh| PDB=1soh | SCENE= }} | ||
===The structure of human apolipoprotein C-II in dodecyl phosphocholine=== | |||
{{ABSTRACT_PUBMED_15209504}} | |||
=== | ==Disease== | ||
[[http://www.uniprot.org/uniprot/APOC2_HUMAN APOC2_HUMAN]] Defects in APOC2 are the cause of hyperlipoproteinemia type 1B (HLPP1B) [MIM:[http://omim.org/entry/207750 207750]]. It is an autosomal recessive trait characterized by hypertriglyceridemia, xanthomas, and increased risk of pancreatitis and early atherosclerosis.<ref>PMID:8323539</ref> | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/APOC2_HUMAN APOC2_HUMAN]] Component of the very low density lipoprotein (VLDL) fraction in plasma, and is an activator of several triacylglycerol lipases. The association of APOC2 with plasma chylomicrons, VLDL, and HDL is reversible, a function of the secretion and catabolism of triglyceride-rich lipoproteins, and changes rapidly. | |||
==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
<ref group="xtra">PMID:015209504</ref><references group="xtra"/> | <ref group="xtra">PMID:015209504</ref><references group="xtra"/><references/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Gooley, P R.]] | [[Category: Gooley, P R.]] | ||
