Sandbox Reserved 709: Difference between revisions
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Here, as the structure begins at the amino acid number 70, we cannot see the IBB which is located in the 2-60 region. | Here, as the structure begins at the amino acid number 70, we cannot see the IBB which is located in the 2-60 region. | ||
* '''A 50kDa C-terminal''' <scene name='Sandbox_Reserved_709/Importin_nlsbs/1'>NLS binding sites</scene> contained in <scene name='Sandbox_Reserved_709/Importin_arm/3'>10 tandem armadillo (Arm) repeats</scene>. These arm repeat domains have an elongated superhelical structure and each of them contains 3 α-helices (H1, H2, H3). Together, H3 helices define the inner concave surface of the protein and the NLS-binding sites. Indeed, in fact there are two NLS-binding sites : a major one and a minor one (determined by their affinity for NLS). | * '''A 50kDa C-terminal''' <scene name='Sandbox_Reserved_709/Importin_nlsbs/1'>NLS binding sites</scene> contained in <scene name='Sandbox_Reserved_709/Importin_arm/3'>10 tandem armadillo (Arm) repeats</scene>. These arm repeat domains have an elongated superhelical structure and each of them contains 3 α-helices (H1, H2, H3). Together, H3 helices define the inner concave surface of the protein and the NLS-binding sites. Indeed, in fact there are two NLS-binding sites : a major one and a minor one (determined by their affinity for NLS). <ref>PMID:22248489</ref> | ||
Here you can see a <scene name='Sandbox_Reserved_709/Nls_basic/1'>NLS </scene>bound to the NLS-binding site of importin α. | Here you can see a <scene name='Sandbox_Reserved_709/Nls_basic/1'>NLS </scene>bound to the NLS-binding site of importin α. | ||
