1tpv: Difference between revisions

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[[Image:1tpv.jpg|left|200px]]<br /><applet load="1tpv" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1tpv.jpg|left|200px]]
caption="1tpv, resolution 1.9&Aring;" />
 
'''S96P CHANGE IS A SECOND-SITE SUPPRESSOR FOR H95N SLUGGISH MUTANT TRIOSEPHOSPHATE ISOMERASE'''<br />
{{Structure
|PDB= 1tpv |SIZE=350|CAPTION= <scene name='initialview01'>1tpv</scene>, resolution 1.9&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=PGH:PHOSPHOGLYCOLOHYDROXAMIC ACID'>PGH</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Triose-phosphate_isomerase Triose-phosphate isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.1.1 5.3.1.1]
|GENE=
}}
 
'''S96P CHANGE IS A SECOND-SITE SUPPRESSOR FOR H95N SLUGGISH MUTANT TRIOSEPHOSPHATE ISOMERASE'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1TPV is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus] with <scene name='pdbligand=PGH:'>PGH</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Triose-phosphate_isomerase Triose-phosphate isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.1.1 5.3.1.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TPV OCA].  
1TPV is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TPV OCA].  


==Reference==
==Reference==
The structural basis for pseudoreversion of the H95N lesion by the secondary S96P mutation in triosephosphate isomerase., Komives EA, Lougheed JC, Zhang Z, Sugio S, Narayana N, Xuong NH, Petsko GA, Ringe D, Biochemistry. 1996 Dec 3;35(48):15474-84. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=8952501 8952501]
The structural basis for pseudoreversion of the H95N lesion by the secondary S96P mutation in triosephosphate isomerase., Komives EA, Lougheed JC, Zhang Z, Sugio S, Narayana N, Xuong NH, Petsko GA, Ringe D, Biochemistry. 1996 Dec 3;35(48):15474-84. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8952501 8952501]
[[Category: Gallus gallus]]
[[Category: Gallus gallus]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: isomerase(intramolecular oxidoreductase)]]
[[Category: isomerase(intramolecular oxidoreductase)]]


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