1tr7: Difference between revisions

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[[Image:1tr7.gif|left|200px]]<br /><applet load="1tr7" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1tr7.gif|left|200px]]
caption="1tr7, resolution 2.10&Aring;" />
 
'''FimH adhesin receptor binding domain from uropathogenic E. coli'''<br />
{{Structure
|PDB= 1tr7 |SIZE=350|CAPTION= <scene name='initialview01'>1tr7</scene>, resolution 2.10&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=CAC:CACODYLATE+ION'>CAC</scene>, <scene name='pdbligand=DEG:BUTYL+ALPHA-D-MANNOPYRANOSIDE'>DEG</scene> and <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>
|ACTIVITY=
|GENE=
}}
 
'''FimH adhesin receptor binding domain from uropathogenic E. coli'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1TR7 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=CAC:'>CAC</scene>, <scene name='pdbligand=DEG:'>DEG</scene> and <scene name='pdbligand=MPD:'>MPD</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TR7 OCA].  
1TR7 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TR7 OCA].  


==Reference==
==Reference==
Receptor binding studies disclose a novel class of high-affinity inhibitors of the Escherichia coli FimH adhesin., Bouckaert J, Berglund J, Schembri M, De Genst E, Cools L, Wuhrer M, Hung CS, Pinkner J, Slattegard R, Zavialov A, Choudhury D, Langermann S, Hultgren SJ, Wyns L, Klemm P, Oscarson S, Knight SD, De Greve H, Mol Microbiol. 2005 Jan;55(2):441-55. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15659162 15659162]
Receptor binding studies disclose a novel class of high-affinity inhibitors of the Escherichia coli FimH adhesin., Bouckaert J, Berglund J, Schembri M, De Genst E, Cools L, Wuhrer M, Hung CS, Pinkner J, Slattegard R, Zavialov A, Choudhury D, Langermann S, Hultgren SJ, Wyns L, Klemm P, Oscarson S, Knight SD, De Greve H, Mol Microbiol. 2005 Jan;55(2):441-55. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15659162 15659162]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: carbohydrate binding]]
[[Category: carbohydrate binding]]
[[Category: type-1 pili]]
[[Category: type-1 pili]]
[[Category: urinary tract infections]]
[[Category: urinary tract infection]]
[[Category: uropathogenic e. coli]]
[[Category: uropathogenic e. coli]]


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