1tv6: Difference between revisions

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[[Image:1tv6.jpg|left|200px]]<br /><applet load="1tv6" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1tv6.jpg|left|200px]]
caption="1tv6, resolution 2.80&Aring;" />
 
'''HIV-1 Reverse Transcriptase Complexed with CP-94,707'''<br />
{{Structure
|PDB= 1tv6 |SIZE=350|CAPTION= <scene name='initialview01'>1tv6</scene>, resolution 2.80&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=CP9:3-[4-(2-METHYL-IMIDAZO[4,5-C]PYRIDIN-1-YL)BENZYL]-3H-BENZOTHIAZOL-2-ONE'>CP9</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Sulfate_adenylyltransferase Sulfate adenylyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.4 2.7.7.4]
|GENE= POL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id= Human immunodeficiency virus type 1 (isolate BH10)])
}}
 
'''HIV-1 Reverse Transcriptase Complexed with CP-94,707'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1TV6 is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_type_1_(isolate_bh10) Human immunodeficiency virus type 1 (isolate bh10)] with <scene name='pdbligand=CP9:'>CP9</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Sulfate_adenylyltransferase Sulfate adenylyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.4 2.7.7.4] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TV6 OCA].  
1TV6 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_type_1_(isolate_bh10) Human immunodeficiency virus type 1 (isolate bh10)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TV6 OCA].  


==Reference==
==Reference==
Structure of HIV-1 reverse transcriptase bound to an inhibitor active against mutant reverse transcriptases resistant to other nonnucleoside inhibitors., Pata JD, Stirtan WG, Goldstein SW, Steitz TA, Proc Natl Acad Sci U S A. 2004 Jul 20;101(29):10548-53. Epub 2004 Jul 12. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15249669 15249669]
Structure of HIV-1 reverse transcriptase bound to an inhibitor active against mutant reverse transcriptases resistant to other nonnucleoside inhibitors., Pata JD, Stirtan WG, Goldstein SW, Steitz TA, Proc Natl Acad Sci U S A. 2004 Jul 20;101(29):10548-53. Epub 2004 Jul 12. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15249669 15249669]
[[Category: Human immunodeficiency virus type 1 (isolate bh10)]]
[[Category: Human immunodeficiency virus type 1 (isolate bh10)]]
[[Category: Protein complex]]
[[Category: Protein complex]]
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[[Category: transferase]]
[[Category: transferase]]


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