1tw2: Difference between revisions

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[[Image:1tw2.gif|left|200px]]<br /><applet load="1tw2" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1tw2.gif|left|200px]]
caption="1tw2, resolution 2.50&Aring;" />
 
'''Crystal structure of Carminomycin-4-O-methyltransferase (DnrK) in complex with S-adenosyl-L-homocystein (SAH) and 4-methoxy-e-rhodomycin T (M-ET)'''<br />
{{Structure
|PDB= 1tw2 |SIZE=350|CAPTION= <scene name='initialview01'>1tw2</scene>, resolution 2.50&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene> and <scene name='pdbligand=ERT:METHYL (4R)-2-ETHYL-2,5,12-TRIHYDROXY-7-METHOXY-6,11-DIOXO-4-{[2,3,6-TRIDEOXY-3-(DIMETHYLAMINO)-BETA-D-RIBO-HEXOPYRANOSYL]OXY}-1H,2H,3H,4H,6H,11H-TETRACENE-1-CARBOXYLATE'>ERT</scene>
|ACTIVITY=
|GENE= dnrk ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1950 Streptomyces peucetius])
}}
 
'''Crystal structure of Carminomycin-4-O-methyltransferase (DnrK) in complex with S-adenosyl-L-homocystein (SAH) and 4-methoxy-e-rhodomycin T (M-ET)'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1TW2 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Streptomyces_peucetius Streptomyces peucetius] with <scene name='pdbligand=SAH:'>SAH</scene> and <scene name='pdbligand=ERT:'>ERT</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TW2 OCA].  
1TW2 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Streptomyces_peucetius Streptomyces peucetius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TW2 OCA].  


==Reference==
==Reference==
Crystal structure of a ternary complex of DnrK, a methyltransferase in daunorubicin biosynthesis, with bound products., Jansson A, Koskiniemi H, Mantsala P, Niemi J, Schneider G, J Biol Chem. 2004 Sep 24;279(39):41149-56. Epub 2004 Jul 24. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15273252 15273252]
Crystal structure of a ternary complex of DnrK, a methyltransferase in daunorubicin biosynthesis, with bound products., Jansson A, Koskiniemi H, Mantsala P, Niemi J, Schneider G, J Biol Chem. 2004 Sep 24;279(39):41149-56. Epub 2004 Jul 24. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15273252 15273252]
[[Category: Single protein]]
[[Category: Single protein]]
[[Category: Streptomyces peucetius]]
[[Category: Streptomyces peucetius]]
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[[Category: s-adenosyl-l-homocystein]]
[[Category: s-adenosyl-l-homocystein]]
[[Category: spine]]
[[Category: spine]]
[[Category: streptomyces]]
[[Category: streptomyce]]
[[Category: structural genomics]]
[[Category: structural genomic]]
[[Category: structural proteomics in europe]]
[[Category: structural proteomics in europe]]
[[Category: tailoring enzyme]]
[[Category: tailoring enzyme]]


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