1twc: Difference between revisions

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[[Image:1twc.gif|left|200px]]<br /><applet load="1twc" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1twc.gif|left|200px]]
caption="1twc, resolution 3.0&Aring;" />
 
'''RNA polymerase II complexed with GTP'''<br />
{{Structure
|PDB= 1twc |SIZE=350|CAPTION= <scene name='initialview01'>1twc</scene>, resolution 3.0&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene> and <scene name='pdbligand=GTP:GUANOSINE-5'-TRIPHOSPHATE'>GTP</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/DNA-directed_RNA_polymerase DNA-directed RNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.6 2.7.7.6]
|GENE=
}}
 
'''RNA polymerase II complexed with GTP'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1TWC is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae] with <scene name='pdbligand=ZN:'>ZN</scene>, <scene name='pdbligand=MN:'>MN</scene> and <scene name='pdbligand=GTP:'>GTP</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/DNA-directed_RNA_polymerase DNA-directed RNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.6 2.7.7.6] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TWC OCA].  
1TWC is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TWC OCA].  


==Reference==
==Reference==
Structural basis of transcription: nucleotide selection by rotation in the RNA polymerase II active center., Westover KD, Bushnell DA, Kornberg RD, Cell. 2004 Nov 12;119(4):481-9. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15537538 15537538]
Structural basis of transcription: nucleotide selection by rotation in the RNA polymerase II active center., Westover KD, Bushnell DA, Kornberg RD, Cell. 2004 Nov 12;119(4):481-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15537538 15537538]
[[Category: DNA-directed RNA polymerase]]
[[Category: DNA-directed RNA polymerase]]
[[Category: Protein complex]]
[[Category: Protein complex]]
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[[Category: multiprotein complex]]
[[Category: multiprotein complex]]
[[Category: transcription]]
[[Category: transcription]]
[[Category: zinc motifs]]
[[Category: zinc motif]]


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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 14:24:06 2008''
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