1twf: Difference between revisions

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[[Image:1twf.gif|left|200px]]<br /><applet load="1twf" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1twf.gif|left|200px]]
caption="1twf, resolution 2.3&Aring;" />
 
'''RNA polymerase II complexed with UTP at 2.3 A resolution'''<br />
{{Structure
|PDB= 1twf |SIZE=350|CAPTION= <scene name='initialview01'>1twf</scene>, resolution 2.3&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene> and <scene name='pdbligand=UTP:URIDINE 5'-TRIPHOSPHATE'>UTP</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/DNA-directed_RNA_polymerase DNA-directed RNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.6 2.7.7.6]
|GENE=
}}
 
'''RNA polymerase II complexed with UTP at 2.3 A resolution'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1TWF is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae] with <scene name='pdbligand=ZN:'>ZN</scene>, <scene name='pdbligand=MN:'>MN</scene> and <scene name='pdbligand=UTP:'>UTP</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/DNA-directed_RNA_polymerase DNA-directed RNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.6 2.7.7.6] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TWF OCA].  
1TWF is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TWF OCA].  


==Reference==
==Reference==
Structural basis of transcription: nucleotide selection by rotation in the RNA polymerase II active center., Westover KD, Bushnell DA, Kornberg RD, Cell. 2004 Nov 12;119(4):481-9. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15537538 15537538]
Structural basis of transcription: nucleotide selection by rotation in the RNA polymerase II active center., Westover KD, Bushnell DA, Kornberg RD, Cell. 2004 Nov 12;119(4):481-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15537538 15537538]
[[Category: DNA-directed RNA polymerase]]
[[Category: DNA-directed RNA polymerase]]
[[Category: Protein complex]]
[[Category: Protein complex]]
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[[Category: multiprotein complex]]
[[Category: multiprotein complex]]
[[Category: transcription]]
[[Category: transcription]]
[[Category: zinc motifs]]
[[Category: zinc motif]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 15:18:04 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 14:24:08 2008''
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