1tww: Difference between revisions

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[[Image:1tww.jpg|left|200px]]<br /><applet load="1tww" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1tww.jpg|left|200px]]
caption="1tww, resolution 2.5&Aring;" />
 
'''Dihydropteroate Synthetase, With Bound Substrate Analogue PtPP, From Bacillus anthracis'''<br />
{{Structure
|PDB= 1tww |SIZE=350|CAPTION= <scene name='initialview01'>1tww</scene>, resolution 2.5&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> and <scene name='pdbligand=HH2:6-HYDROXYMETHYLPTERIN-DIPHOSPHATE'>HH2</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Dihydropteroate_synthase Dihydropteroate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.15 2.5.1.15]
|GENE= folp ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=191218 Bacillus anthracis str. A2012])
}}
 
'''Dihydropteroate Synthetase, With Bound Substrate Analogue PtPP, From Bacillus anthracis'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1TWW is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_anthracis_str._a2012 Bacillus anthracis str. a2012] with <scene name='pdbligand=SO4:'>SO4</scene> and <scene name='pdbligand=HH2:'>HH2</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Dihydropteroate_synthase Dihydropteroate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.15 2.5.1.15] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TWW OCA].  
1TWW is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_anthracis_str._a2012 Bacillus anthracis str. a2012]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TWW OCA].  


==Reference==
==Reference==
Crystal structure of 7,8-dihydropteroate synthase from Bacillus anthracis: mechanism and novel inhibitor design., Babaoglu K, Qi J, Lee RE, White SW, Structure. 2004 Sep;12(9):1705-17. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15341734 15341734]
Crystal structure of 7,8-dihydropteroate synthase from Bacillus anthracis: mechanism and novel inhibitor design., Babaoglu K, Qi J, Lee RE, White SW, Structure. 2004 Sep;12(9):1705-17. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15341734 15341734]
[[Category: Bacillus anthracis str. a2012]]
[[Category: Bacillus anthracis str. a2012]]
[[Category: Dihydropteroate synthase]]
[[Category: Dihydropteroate synthase]]
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[[Category: pterine]]
[[Category: pterine]]


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