1txi: Difference between revisions

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[[Image:1txi.gif|left|200px]]<br /><applet load="1txi" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1txi.gif|left|200px]]
caption="1txi, resolution 1.9&Aring;" />
 
'''Crystal structure of the vdr ligand binding domain complexed to TX522'''<br />
{{Structure
|PDB= 1txi |SIZE=350|CAPTION= <scene name='initialview01'>1txi</scene>, resolution 1.9&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=TX5:(1R,3R)-5-((Z)-2-((1R,7AS)-HEXAHYDRO-1-((S)-6-HYDROXY-6-METHYLHEPT-4-YN-2-YL)-7A-METHYL-1H-INDEN-4(7AH)-YLIDENE)ETHYLIDENE)CYCLOHEXANE-1,3-DIOL'>TX5</scene>
|ACTIVITY=
|GENE= NR1I1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Crystal structure of the vdr ligand binding domain complexed to TX522'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1TXI is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=TX5:'>TX5</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TXI OCA].  
1TXI is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TXI OCA].  


==Reference==
==Reference==
Superagonistic action of 14-epi-analogs of 1,25-dihydroxyvitamin D explained by vitamin D receptor-coactivator interaction., Eelen G, Verlinden L, Rochel N, Claessens F, De Clercq P, Vandewalle M, Tocchini-Valentini G, Moras D, Bouillon R, Verstuyf A, Mol Pharmacol. 2005 May;67(5):1566-73. Epub 2005 Feb 22. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15728261 15728261]
Superagonistic action of 14-epi-analogs of 1,25-dihydroxyvitamin D explained by vitamin D receptor-coactivator interaction., Eelen G, Verlinden L, Rochel N, Claessens F, De Clercq P, Vandewalle M, Tocchini-Valentini G, Moras D, Bouillon R, Verstuyf A, Mol Pharmacol. 2005 May;67(5):1566-73. Epub 2005 Feb 22. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15728261 15728261]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: vdr ligand binding domain]]
[[Category: vdr ligand binding domain]]


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