1tz8: Difference between revisions

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[[Image:1tz8.gif|left|200px]]<br /><applet load="1tz8" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1tz8.gif|left|200px]]
caption="1tz8, resolution 1.85&Aring;" />
 
'''The monoclinic crystal struture of transthyretin in complex with diethylstilbestrol'''<br />
{{Structure
|PDB= 1tz8 |SIZE=350|CAPTION= <scene name='initialview01'>1tz8</scene>, resolution 1.85&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=CO3:CARBONATE+ION'>CO3</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=DES:DIETHYLSTILBESTROL'>DES</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
|ACTIVITY=
|GENE= TTR, PALB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''The monoclinic crystal struture of transthyretin in complex with diethylstilbestrol'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1TZ8 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=CO3:'>CO3</scene>, <scene name='pdbligand=ACT:'>ACT</scene>, <scene name='pdbligand=DMS:'>DMS</scene>, <scene name='pdbligand=DES:'>DES</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TZ8 OCA].  
1TZ8 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TZ8 OCA].  


==Reference==
==Reference==
The crystal structure of transthyretin in complex with diethylstilbestrol: a promising template for the design of amyloid inhibitors., Morais-de-Sa E, Pereira PJ, Saraiva MJ, Damas AM, J Biol Chem. 2004 Dec 17;279(51):53483-90. Epub 2004 Oct 6. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15469931 15469931]
The crystal structure of transthyretin in complex with diethylstilbestrol: a promising template for the design of amyloid inhibitors., Morais-de-Sa E, Pereira PJ, Saraiva MJ, Damas AM, J Biol Chem. 2004 Dec 17;279(51):53483-90. Epub 2004 Oct 6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15469931 15469931]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: transthyretin]]
[[Category: transthyretin]]


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