1u0w: Difference between revisions

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[[Image:1u0w.gif|left|200px]]<br /><applet load="1u0w" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1u0w.gif|left|200px]]
caption="1u0w, resolution 2.00&Aring;" />
 
'''An Aldol Switch Discovered in Stilbene Synthases Mediates Cyclization Specificity of Type III Polyketide Synthases: 18xCHS+resveratrol Structure'''<br />
{{Structure
|PDB= 1u0w |SIZE=350|CAPTION= <scene name='initialview01'>1u0w</scene>, resolution 2.00&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=STL:RESVERATROL'>STL</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Naringenin-chalcone_synthase Naringenin-chalcone synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.74 2.3.1.74]
|GENE= CHS2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3879 Medicago sativa])
}}
 
'''An Aldol Switch Discovered in Stilbene Synthases Mediates Cyclization Specificity of Type III Polyketide Synthases: 18xCHS+resveratrol Structure'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1U0W is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Medicago_sativa Medicago sativa] with <scene name='pdbligand=STL:'>STL</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Naringenin-chalcone_synthase Naringenin-chalcone synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.74 2.3.1.74] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U0W OCA].  
1U0W is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Medicago_sativa Medicago sativa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U0W OCA].  


==Reference==
==Reference==
An aldol switch discovered in stilbene synthases mediates cyclization specificity of type III polyketide synthases., Austin MB, Bowman ME, Ferrer JL, Schroder J, Noel JP, Chem Biol. 2004 Sep;11(9):1179-94. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15380179 15380179]
An aldol switch discovered in stilbene synthases mediates cyclization specificity of type III polyketide synthases., Austin MB, Bowman ME, Ferrer JL, Schroder J, Noel JP, Chem Biol. 2004 Sep;11(9):1179-94. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15380179 15380179]
[[Category: Medicago sativa]]
[[Category: Medicago sativa]]
[[Category: Naringenin-chalcone synthase]]
[[Category: Naringenin-chalcone synthase]]
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[[Category: catalytic triad]]
[[Category: catalytic triad]]
[[Category: chalcone synthase]]
[[Category: chalcone synthase]]
[[Category: chs]]
[[Category: ch]]
[[Category: condensing enzyme]]
[[Category: condensing enzyme]]
[[Category: engineered resveratrol synthase]]
[[Category: engineered resveratrol synthase]]
[[Category: pks]]
[[Category: pk]]
[[Category: rs]]
[[Category: r]]
[[Category: stilbene synthase]]
[[Category: stilbene synthase]]
[[Category: sts]]
[[Category: st]]
[[Category: thiolase fold]]
[[Category: thiolase fold]]
[[Category: type iii polyketide synthase]]
[[Category: type iii polyketide synthase]]


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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 14:25:54 2008''
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