1u4o: Difference between revisions

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[[Image:1u4o.gif|left|200px]]<br /><applet load="1u4o" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1u4o.gif|left|200px]]
caption="1u4o, resolution 1.70&Aring;" />
 
'''Plasmodium falciparum lactate dehydrogenase complexed with 2,6-naphthalenedicarboxylic acid'''<br />
{{Structure
|PDB= 1u4o |SIZE=350|CAPTION= <scene name='initialview01'>1u4o</scene>, resolution 1.70&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=NDD:2,6-DICARBOXYNAPHTHALENE'>NDD</scene> and <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/L-lactate_dehydrogenase L-lactate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.27 1.1.1.27]
|GENE=
}}
 
'''Plasmodium falciparum lactate dehydrogenase complexed with 2,6-naphthalenedicarboxylic acid'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1U4O is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum] with <scene name='pdbligand=NDD:'>NDD</scene> and <scene name='pdbligand=MPD:'>MPD</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/L-lactate_dehydrogenase L-lactate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.27 1.1.1.27] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U4O OCA].  
1U4O is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U4O OCA].  


==Reference==
==Reference==
Mapping the binding site for gossypol-like inhibitors of Plasmodium falciparum lactate dehydrogenase., Conners R, Schambach F, Read J, Cameron A, Sessions RB, Vivas L, Easton A, Croft SL, Brady RL, Mol Biochem Parasitol. 2005 Aug;142(2):137-48. Epub 2005 Apr 18. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15978953 15978953]
Mapping the binding site for gossypol-like inhibitors of Plasmodium falciparum lactate dehydrogenase., Conners R, Schambach F, Read J, Cameron A, Sessions RB, Vivas L, Easton A, Croft SL, Brady RL, Mol Biochem Parasitol. 2005 Aug;142(2):137-48. Epub 2005 Apr 18. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15978953 15978953]
[[Category: L-lactate dehydrogenase]]
[[Category: L-lactate dehydrogenase]]
[[Category: Plasmodium falciparum]]
[[Category: Plasmodium falciparum]]
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[[Category: protein-ligand complex]]
[[Category: protein-ligand complex]]


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