1u67: Difference between revisions

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[[Image:1u67.jpg|left|200px]]<br /><applet load="1u67" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1u67.jpg|left|200px]]
caption="1u67, resolution 3.1&Aring;" />
 
'''Crystal Structure of Arachidonic Acid Bound to a Mutant of Prostagladin H Synthase-1 that Forms Predominantly 11-HPETE.'''<br />
{{Structure
|PDB= 1u67 |SIZE=350|CAPTION= <scene name='initialview01'>1u67</scene>, resolution 3.1&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=BOG:B-OCTYLGLUCOSIDE'>BOG</scene>, <scene name='pdbligand=COH:PROTOPORPHYRIN+IX+CONTAINING+CO'>COH</scene> and <scene name='pdbligand=ACD:ARACHIDONIC ACID'>ACD</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Prostaglandin-endoperoxide_synthase Prostaglandin-endoperoxide synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.99.1 1.14.99.1]
|GENE= PTGS1, COX1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9940 Ovis aries])
}}
 
'''Crystal Structure of Arachidonic Acid Bound to a Mutant of Prostagladin H Synthase-1 that Forms Predominantly 11-HPETE.'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1U67 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Ovis_aries Ovis aries] with <scene name='pdbligand=BOG:'>BOG</scene>, <scene name='pdbligand=COH:'>COH</scene> and <scene name='pdbligand=ACD:'>ACD</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Prostaglandin-endoperoxide_synthase Prostaglandin-endoperoxide synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.99.1 1.14.99.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U67 OCA].  
1U67 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Ovis_aries Ovis aries]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U67 OCA].  


==Reference==
==Reference==
Crystal structure of arachidonic acid bound to a mutant of prostaglandin endoperoxide H synthase-1 that forms predominantly 11-hydroperoxyeicosatetraenoic acid., Harman CA, Rieke CJ, Garavito RM, Smith WL, J Biol Chem. 2004 Oct 8;279(41):42929-35. Epub 2004 Jul 30. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15292194 15292194]
Crystal structure of arachidonic acid bound to a mutant of prostaglandin endoperoxide H synthase-1 that forms predominantly 11-hydroperoxyeicosatetraenoic acid., Harman CA, Rieke CJ, Garavito RM, Smith WL, J Biol Chem. 2004 Oct 8;279(41):42929-35. Epub 2004 Jul 30. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15292194 15292194]
[[Category: Ovis aries]]
[[Category: Ovis aries]]
[[Category: Prostaglandin-endoperoxide synthase]]
[[Category: Prostaglandin-endoperoxide synthase]]
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[[Category: heme]]
[[Category: heme]]


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