1uaq: Difference between revisions

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[[Image:1uaq.gif|left|200px]]<br /><applet load="1uaq" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1uaq.gif|left|200px]]
caption="1uaq, resolution 1.6&Aring;" />
 
'''The crystal structure of yeast cytosine deaminase'''<br />
{{Structure
|PDB= 1uaq |SIZE=350|CAPTION= <scene name='initialview01'>1uaq</scene>, resolution 1.6&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene> and <scene name='pdbligand=DUC:DIHYDROPYRIMIDINE-2,4(1H,3H)-DIONE'>DUC</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Cytosine_deaminase Cytosine deaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.4.1 3.5.4.1]
|GENE= fcy1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])
}}
 
'''The crystal structure of yeast cytosine deaminase'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1UAQ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae] with <scene name='pdbligand=ZN:'>ZN</scene> and <scene name='pdbligand=DUC:'>DUC</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Cytosine_deaminase Cytosine deaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.4.1 3.5.4.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UAQ OCA].  
1UAQ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UAQ OCA].  


==Reference==
==Reference==
Crystal structure of yeast cytosine deaminase. Insights into enzyme mechanism and evolution., Ko TP, Lin JJ, Hu CY, Hsu YH, Wang AH, Liaw SH, J Biol Chem. 2003 May 23;278(21):19111-7. Epub 2003 Mar 13. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12637534 12637534]
Crystal structure of yeast cytosine deaminase. Insights into enzyme mechanism and evolution., Ko TP, Lin JJ, Hu CY, Hsu YH, Wang AH, Liaw SH, J Biol Chem. 2003 May 23;278(21):19111-7. Epub 2003 Mar 13. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12637534 12637534]
[[Category: Cytosine deaminase]]
[[Category: Cytosine deaminase]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: alpha-beta-alpha]]
[[Category: alpha-beta-alpha]]


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