1ugv: Difference between revisions
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{{STRUCTURE_1ugv| PDB=1ugv | SCENE= }} | {{STRUCTURE_1ugv| PDB=1ugv | SCENE= }} | ||
===Solution structure of the SH3 domain of human olygophrein-1 like protein (KIAA0621)=== | |||
=== | ==Disease== | ||
[[http://www.uniprot.org/uniprot/RHG26_HUMAN RHG26_HUMAN]] Defects in ARHGAP26 are a cause of juvenile myelomonocytic leukemia (JMML) [MIM:[http://omim.org/entry/607785 607785]]. JMML is a pediatric myelodysplastic syndrome that constitutes approximately 30% of childhood cases of myelodysplastic syndrome (MDS) and 2% of leukemia. Chromosomal translocation t(5;11)(q31;q23) with MLL has been found in a JMML patient. | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/RHG26_HUMAN RHG26_HUMAN]] GTPase-activating protein for RHOA and CDC42. | |||
==About this Structure== | ==About this Structure== | ||
