Sandbox Reserved 706: Difference between revisions
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The structure of Rab27B in the complex contains a <scene name='Sandbox_Reserved_706/Beta_1_a_6_sans_annotation/1'>central six stranded beta sheet</scene> (ß1-6) flanked by <scene name='Sandbox_Reserved_706/Alpha_1_a_5/2'>five alpha helices </scene>(α1–5). Like other Ras-like small GTPases, Rab27B binds with <scene name='Sandbox_Reserved_706/Gtp_ligant/1'>GTP</scene> and <scene name='Sandbox_Reserved_706/Mg_ligand/1'>Mg2+</scene> in the conserved nucleotide-binding site (also see figure 2). | The structure of Rab27B in the complex contains a <scene name='Sandbox_Reserved_706/Beta_1_a_6_sans_annotation/1'>central six stranded beta sheet</scene> (ß1-6) flanked by <scene name='Sandbox_Reserved_706/Alpha_1_a_5/2'>five alpha helices </scene>(α1–5). Like other Ras-like small GTPases, Rab27B binds with <scene name='Sandbox_Reserved_706/Gtp_ligant/1'>GTP</scene> and <scene name='Sandbox_Reserved_706/Mg_ligand/1'>Mg2+</scene> in the conserved nucleotide-binding site (also see figure 2). | ||
Rab27B adopt a globular form in the complex. The | Rab27B adopt a globular form in the complex. The | ||
<scene name='Sandbox_Reserved_706/Loop_entre_beta_2_et_3/1'>ß2 and ß3 loop(residues 55-64)</scene> and α3-ß5 loop (residues122-126) of Rab27B are both regions involved in Slac2-a binding. <ref>PMID:18940604</ref> | <scene name='Sandbox_Reserved_706/Loop_entre_beta_2_et_3/1'>ß2 and ß3 loop (residues 55-64)</scene> and <scene name='Sandbox_Reserved_706/Rab27b_loop_2_alpha3_b5/1'>α3-ß5 loop (residues122-126)</scene> of Rab27B are both regions involved in Slac2-a binding. <ref>PMID:18940604</ref> | ||
