1yo8: Difference between revisions
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{{STRUCTURE_1yo8| PDB=1yo8 | SCENE= }} | {{STRUCTURE_1yo8| PDB=1yo8 | SCENE= }} | ||
===Structure of the C-terminal domain of human thrombospondin-2=== | |||
{{ABSTRACT_PUBMED_16186819}} | |||
=== | ==Disease== | ||
[[http://www.uniprot.org/uniprot/TSP2_HUMAN TSP2_HUMAN]] Genetic variations in THBS2 may be a cause of susceptibility to intervertebral disk disease (IDD) [MIM:[http://omim.org/entry/603932 603932]]; also known as lumbar disk herniation (LDH). IDD is one of the most common musculo-skeletal disorders and the predominant cause of low-back pain and unilateral leg pain.<ref>PMID:18455130</ref> | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/TSP2_HUMAN TSP2_HUMAN]] Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Ligand for CD36 mediating antiangiogenic properties.<ref>PMID:20714802</ref> | |||
==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
<ref group="xtra">PMID:016186819</ref><references group="xtra"/> | <ref group="xtra">PMID:016186819</ref><references group="xtra"/><references/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Annis, D S.]] | [[Category: Annis, D S.]] | ||
