1ung: Difference between revisions

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[[Image:1ung.gif|left|200px]]<br /><applet load="1ung" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1ung.gif|left|200px]]
caption="1ung, resolution 2.30&Aring;" />
 
'''STRUCTURAL MECHANISM FOR THE INHIBITION OF CDK5-P25 BY ROSCOVITINE, ALOISINE AND INDIRUBIN.'''<br />
{{Structure
|PDB= 1ung |SIZE=350|CAPTION= <scene name='initialview01'>1ung</scene>, resolution 2.30&Aring;
|SITE= <scene name='pdbsite=AC1:Alh+Binding+Site+For+Chain+B'>AC1</scene>
|LIGAND= <scene name='pdbligand=ALH:6-PHENYL[5H]PYRROLO[2,3-B]PYRAZINE'>ALH</scene>
|ACTIVITY=
|GENE=
}}
 
'''STRUCTURAL MECHANISM FOR THE INHIBITION OF CDK5-P25 BY ROSCOVITINE, ALOISINE AND INDIRUBIN.'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1UNG is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=ALH:'>ALH</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Known structural/functional Site: <scene name='pdbsite=AC1:Alh+Binding+Site+For+Chain+B'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UNG OCA].  
1UNG is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UNG OCA].  


==Reference==
==Reference==
Mechanism of CDK5/p25 binding by CDK inhibitors., Mapelli M, Massimiliano L, Crovace C, Seeliger MA, Tsai LH, Meijer L, Musacchio A, J Med Chem. 2005 Feb 10;48(3):671-9. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15689152 15689152]
Mechanism of CDK5/p25 binding by CDK inhibitors., Mapelli M, Massimiliano L, Crovace C, Seeliger MA, Tsai LH, Meijer L, Musacchio A, J Med Chem. 2005 Feb 10;48(3):671-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15689152 15689152]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Protein complex]]
[[Category: Protein complex]]
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[[Category: atp-analogue]]
[[Category: atp-analogue]]
[[Category: cyclin dependent kinase]]
[[Category: cyclin dependent kinase]]
[[Category: inhibitors]]
[[Category: inhibitor]]
[[Category: neurodegenerative diseases]]
[[Category: neurodegenerative disease]]


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