1uop: Difference between revisions

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[[Image:1uop.gif|left|200px]]<br /><applet load="1uop" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1uop.gif|left|200px]]
caption="1uop, resolution 1.85&Aring;" />
 
'''PROLYL OLIGOPEPTIDASE FROM PORCINE BRAIN, S554A MUTANT WITH BOUND PEPTIDE LIGAND GLY-PHE-GLU-PRO'''<br />
{{Structure
|PDB= 1uop |SIZE=350|CAPTION= <scene name='initialview01'>1uop</scene>, resolution 1.85&Aring;
|SITE= <scene name='pdbsite=AS1:Peptide+Binding+Site+For+Chain+A'>AS1</scene>
|LIGAND= <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Prolyl_oligopeptidase Prolyl oligopeptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.26 3.4.21.26]
|GENE=
}}
 
'''PROLYL OLIGOPEPTIDASE FROM PORCINE BRAIN, S554A MUTANT WITH BOUND PEPTIDE LIGAND GLY-PHE-GLU-PRO'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1UOP is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa] with <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Prolyl_oligopeptidase Prolyl oligopeptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.26 3.4.21.26] Known structural/functional Site: <scene name='pdbsite=AS1:Peptide+Binding+Site+For+Chain+A'>AS1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UOP OCA].  
1UOP is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UOP OCA].  


==Reference==
==Reference==
Electrostatic environment at the active site of prolyl oligopeptidase is highly influential during substrate binding., Szeltner Z, Rea D, Renner V, Juliano L, Fulop V, Polgar L, J Biol Chem. 2003 Dec 5;278(49):48786-93. Epub 2003 Sep 25. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=14514675 14514675]
Electrostatic environment at the active site of prolyl oligopeptidase is highly influential during substrate binding., Szeltner Z, Rea D, Renner V, Juliano L, Fulop V, Polgar L, J Biol Chem. 2003 Dec 5;278(49):48786-93. Epub 2003 Sep 25. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14514675 14514675]
[[Category: Prolyl oligopeptidase]]
[[Category: Prolyl oligopeptidase]]
[[Category: Protein complex]]
[[Category: Protein complex]]
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[[Category: serine protease]]
[[Category: serine protease]]


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