1uom: Difference between revisions

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[[Image:1uom.gif|left|200px]]~~<br /><applet load~~="1uom~~" size~~="350~~" color~~=~~"white" frame~~=~~"true" align="right" spinBox="true"~~

[[Image:1uom.gif|left|200px]]

~~caption="~~1uom, resolution 2.28Å" />

'''THE STRUCTURE OF ESTROGEN RECEPTOR IN COMPLEX WITH A SELECTIVE AND POTENT TETRAHYDROISOCHIOLIN LIGAND.'''~~<br />~~

{{Structure

|PDB= 1uom |SIZE=350|CAPTION= <scene name='initialview01'>1uom</scene>, resolution 2.28Å

|SITE= <scene name='pdbsite=PTI:Pti+Binding+Site+For+Chain+A'>PTI</scene>

|LIGAND= <scene name='pdbligand=PTI:2-PHENYL-1-[4-(2-PIPERIDIN-1-YL-ETHOXY)-PHENYL]-1,2,3,4-TETRAHYDRO-ISOQUINOLIN-6-OL'>PTI</scene>

|ACTIVITY=

|GENE=

}}

'''THE STRUCTURE OF ESTROGEN RECEPTOR IN COMPLEX WITH A SELECTIVE AND POTENT TETRAHYDROISOCHIOLIN LIGAND.'''

==Overview==

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==About this Structure==

1UOM is a [~~http://en.wikipedia.org/wiki/Single_protein~~ Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] ~~with <scene name='pdbligand=PTI:'>PTI</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Known structural/functional Site: <scene name='pdbsite=PTI:Pti+Binding+Site+For+Chain+A'>PTI</scene>~~. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UOM OCA].

1UOM is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UOM OCA].

==Reference==

Estrogen receptor modulators: identification and structure-activity relationships of potent ERalpha-selective tetrahydroisoquinoline ligands., Renaud J, Bischoff SF, Buhl T, Floersheim P, Fournier B, Halleux C, Kallen J, Keller H, Schlaeppi JM, Stark W, J Med Chem. 2003 Jul 3;46(14):2945-57. PMID:[http://~~ispc~~.~~weizmann~~.ac.~~il/~~/~~pmbin~~/~~getpm?pmid=~~12825935 12825935]

Estrogen receptor modulators: identification and structure-activity relationships of potent ERalpha-selective tetrahydroisoquinoline ligands., Renaud J, Bischoff SF, Buhl T, Floersheim P, Fournier B, Halleux C, Kallen J, Keller H, Schlaeppi JM, Stark W, J Med Chem. 2003 Jul 3;46(14):2945-57. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12825935 12825935]

[[Category: Homo sapiens]]

[[Category: Single protein]]

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[[Category: polymorphism 3d-structure]]

[[Category: receptor]]

[[Category: selective estrogen receptor ~~modulators~~]]

[[Category: selective estrogen receptor modulator]]

[[Category: serm]]

[[Category: steroid-binding]]

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[[Category: zinc-finger]]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu ~~Feb 21 15~~:26:49 2008''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 14:34:49 2008''

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@@ Line 1: / Line 1: @@
-[[Image:1uom.gif|left|200px]]<br /><applet load="1uom" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:1uom.gif|left|200px]]
-caption="1uom, resolution 2.28&Aring;" />
-'''THE STRUCTURE OF ESTROGEN RECEPTOR IN COMPLEX WITH A SELECTIVE AND POTENT TETRAHYDROISOCHIOLIN LIGAND.'''<br />
+ {{Structure
+|PDB= 1uom |SIZE=350|CAPTION= <scene name='initialview01'>1uom</scene>, resolution 2.28&Aring;
+|SITE= <scene name='pdbsite=PTI:Pti+Binding+Site+For+Chain+A'>PTI</scene>
+|LIGAND= <scene name='pdbligand=PTI:2-PHENYL-1-[4-(2-PIPERIDIN-1-YL-ETHOXY)-PHENYL]-1,2,3,4-TETRAHYDRO-ISOQUINOLIN-6-OL'>PTI</scene>
+|ACTIVITY=
+|GENE=
+}}
+'''THE STRUCTURE OF ESTROGEN RECEPTOR IN COMPLEX WITH A SELECTIVE AND POTENT TETRAHYDROISOCHIOLIN LIGAND.'''
 ==Overview==
@@ Line 10: / Line 19: @@
 ==About this Structure==
-UOM is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=PTI:'>PTI</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Known structural/functional Site: <scene name='pdbsite=PTI:Pti+Binding+Site+For+Chain+A'>PTI</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UOM OCA].
+UOM is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UOM OCA].
 ==Reference==
-Estrogen receptor modulators: identification and structure-activity relationships of potent ERalpha-selective tetrahydroisoquinoline ligands., Renaud J, Bischoff SF, Buhl T, Floersheim P, Fournier B, Halleux C, Kallen J, Keller H, Schlaeppi JM, Stark W, J Med Chem. 2003 Jul 3;46(14):2945-57. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12825935 12825935]
+Estrogen receptor modulators: identification and structure-activity relationships of potent ERalpha-selective tetrahydroisoquinoline ligands., Renaud J, Bischoff SF, Buhl T, Floersheim P, Fournier B, Halleux C, Kallen J, Keller H, Schlaeppi JM, Stark W, J Med Chem. 2003 Jul 3;46(14):2945-57. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12825935 12825935]
 [[Category: Homo sapiens]]
 [[Category: Single protein]]
@@ Line 31: / Line 40: @@
 [[Category: polymorphism 3d-structure]]
 [[Category: receptor]]
-[[Category: selective estrogen receptor modulators]]
+[[Category: selective estrogen receptor modulator]]
 [[Category: serm]]
 [[Category: steroid-binding]]
@@ Line 37: / Line 46: @@
 [[Category: zinc-finger]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 15:26:49 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 14:34:49 2008''