1uou: Difference between revisions

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[[Image:1uou.gif|left|200px]]<br /><applet load="1uou" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1uou.gif|left|200px]]
caption="1uou, resolution 2.11&Aring;" />
 
'''CRYSTAL STRUCTURE OF HUMAN THYMIDINE PHOSPHORYLASE IN COMPLEX WITH A SMALL MOLECULE INHIBITOR'''<br />
{{Structure
|PDB= 1uou |SIZE=350|CAPTION= <scene name='initialview01'>1uou</scene>, resolution 2.11&Aring;
|SITE= <scene name='pdbsite=AC1:Cmu+Binding+Site+For+Chain+A'>AC1</scene>
|LIGAND= <scene name='pdbligand=CMU:5-CHLORO-6-(1-(2-IMINOPYRROLIDINYL) METHYL) URACIL'>CMU</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Thymidine_phosphorylase Thymidine phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.4 2.4.2.4]
|GENE=
}}
 
'''CRYSTAL STRUCTURE OF HUMAN THYMIDINE PHOSPHORYLASE IN COMPLEX WITH A SMALL MOLECULE INHIBITOR'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1UOU is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=CMU:'>CMU</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Thymidine_phosphorylase Thymidine phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.4 2.4.2.4] Known structural/functional Site: <scene name='pdbsite=AC1:Cmu+Binding+Site+For+Chain+A'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UOU OCA].  
1UOU is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UOU OCA].  


==Reference==
==Reference==
Crystal structure of human thymidine phosphorylase in complex with a small molecule inhibitor., Norman RA, Barry ST, Bate M, Breed J, Colls JG, Ernill RJ, Luke RW, Minshull CA, McAlister MS, McCall EJ, McMiken HH, Paterson DS, Timms D, Tucker JA, Pauptit RA, Structure. 2004 Jan;12(1):75-84. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=14725767 14725767]
Crystal structure of human thymidine phosphorylase in complex with a small molecule inhibitor., Norman RA, Barry ST, Bate M, Breed J, Colls JG, Ernill RJ, Luke RW, Minshull CA, McAlister MS, McCall EJ, McMiken HH, Paterson DS, Timms D, Tucker JA, Pauptit RA, Structure. 2004 Jan;12(1):75-84. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14725767 14725767]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: transferase]]
[[Category: transferase]]


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