1ur8: Difference between revisions

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[[Image:1ur8.gif|left|200px]]<br /><applet load="1ur8" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1ur8.gif|left|200px]]
caption="1ur8, resolution 1.90&Aring;" />
 
'''INTERACTIONS OF A FAMILY 18 CHITINASE WITH THE DESIGNED INHIBITOR HM508, AND ITS DEGRADATION PRODUCT, CHITOBIONO-DELTA-LACTONE'''<br />
{{Structure
|PDB= 1ur8 |SIZE=350|CAPTION= <scene name='initialview01'>1ur8</scene>, resolution 1.90&Aring;
|SITE= <scene name='pdbsite=GLU:So4+Binding+Site+For+Chain+B'>GLU</scene>
|LIGAND= <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=GDL:2-ACETAMIDO-2-DEOXY-D-GLUCONO-1,5-LACTONE'>GDL</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Chitinase Chitinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.14 3.2.1.14]
|GENE=
}}
 
'''INTERACTIONS OF A FAMILY 18 CHITINASE WITH THE DESIGNED INHIBITOR HM508, AND ITS DEGRADATION PRODUCT, CHITOBIONO-DELTA-LACTONE'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1UR8 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Serratia_marcescens Serratia marcescens] with <scene name='pdbligand=NAG:'>NAG</scene>, <scene name='pdbligand=SO4:'>SO4</scene>, <scene name='pdbligand=GDL:'>GDL</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Chitinase Chitinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.14 3.2.1.14] Known structural/functional Site: <scene name='pdbsite=GLU:So4+Binding+Site+For+Chain+B'>GLU</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UR8 OCA].  
1UR8 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Serratia_marcescens Serratia marcescens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UR8 OCA].  


==Reference==
==Reference==
Interactions of a family 18 chitinase with the designed inhibitor HM508 and its degradation product, chitobiono-delta-lactone., Vaaje-Kolstad G, Vasella A, Peter MG, Netter C, Houston DR, Westereng B, Synstad B, Eijsink VG, van Aalten DM, J Biol Chem. 2004 Jan 30;279(5):3612-9. Epub 2003 Nov 3. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=14597613 14597613]
Interactions of a family 18 chitinase with the designed inhibitor HM508 and its degradation product, chitobiono-delta-lactone., Vaaje-Kolstad G, Vasella A, Peter MG, Netter C, Houston DR, Westereng B, Synstad B, Eijsink VG, van Aalten DM, J Biol Chem. 2004 Jan 30;279(5):3612-9. Epub 2003 Nov 3. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14597613 14597613]
[[Category: Chitinase]]
[[Category: Chitinase]]
[[Category: Serratia marcescens]]
[[Category: Serratia marcescens]]
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[[Category: lactone]]
[[Category: lactone]]


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