Sandbox Reserved 707: Difference between revisions

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[[Image:Reaction catalysed by raf protein family.jpg]]
[[Image:Reaction catalysed by raf protein family.jpg]]


This cascade participates in the regulation of several cellular mechanisms like: apoptosis, cell cycle progression, differentiation, proliferation and transformation to the cancerous state in response to growth factors, cytokines and hormones. First discovered in 1938 as a retroviral oncogene B-RAF plays a key role on all studies concerning cancer therapies and other biomedical applications.  
This cascade participates in the regulation of several cellular mechanisms like: apoptosis, cell cycle progression, differentiation, proliferation and transformation to the cancerous state in response to growth factors, cytokines and hormones. First discovered in 1938<ref>PMID:16649144</ref> as a retroviral oncogene B-RAF plays a key role on all studies concerning cancer therapies and other biomedical applications.  


== B-RAF Structure<ref>PMID: 15035987</ref> ==
== B-RAF Structure<ref>PMID: 15035987</ref> ==